Monatshefte für Chemie - Chemical Monthly

, Volume 149, Issue 11, pp 2113–2121 | Cite as

On the regioselectivity of the amberlyst-15 catalyzed condensation of 2-hydroxychalcones and 4,4-dimethylcyclohexane-1,3-dione

  • Nayim Sepay
  • Sumitava Mallik
  • Chayan Guha
  • Rina Mondal
  • Asok K. MallikEmail author
Original Paper


Amberlyst-15 catalyzed condensation of 2-hydroxychalcones and 4,4-dimethylcyclohexane-1,3-dione in refluxing toluene was found to show regioselectivity resulting in (6R*,12S*)-2,2-dimethyl-6-phenyl-2,3,4,12-tetrahydro-1H-6,12-methanodibenzo[d,g][1,3]dioxocin-1-ones as the major product.

Graphical abstract


2-Hydroxychalcones 4,4-Dimethylcyclohexane-1,3-dione Amberlyst-15 Regioselective condensation (6R*,12S*)-2,2-Dimethyl-6-phenyl-2,3,4,12-tetrahydro-1H-6,12-methanodibenzo[d,g][1,3]dioxocin-1-ones 



Financial support and spectral facilities from the PURSE and FIST programs of the DST and CAS program of the UGC, New Delhi to the Department of Chemistry, Jadavpur University are gratefully acknowledged. The UPE-II program of the UGC is also thanked for financial assistance. N.S., S.M., C.G. and R.M. are thankful to the UGC, New Delhi for their Research Fellowships.

Supplementary material

706_2018_2258_MOESM1_ESM.pdf (2.7 mb)
Supplementary material 1 (PDF 2779 kb)


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • Nayim Sepay
    • 1
  • Sumitava Mallik
    • 1
  • Chayan Guha
    • 1
  • Rina Mondal
    • 1
  • Asok K. Mallik
    • 1
    Email author
  1. 1.Department of ChemistryJadavpur UniversityKolkataIndia

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