Archives of Virology

, Volume 164, Issue 10, pp 2551–2558 | Cite as

Discovery of a virus of the species Enterovirus F in goats

  • Xiaoran Chang
  • Qian Lin
  • Junying Hu
  • Xu Wang
  • Xin Li
  • Menglu Cai
  • Weiyu Wang
  • Zecai Zhang
  • Xinping WangEmail author
Brief Report


Here, we report two novel enteroviruses, designated as SD-S67 and SD-S68, isolated from a goat farm. Their complete genome sequences were determined and found to be 7455 and 7465 nucleotides in length, respectively. Molecular characterization revealed that SD-S67 is closely related to bovine enterovirus strain 261 and that SD-S68 to caprine enterovirus strain CEV-JL14. Phylogenetic analysis showed that SD-S67 clustered with members of the species Enterovirus F, and that SD-S68 clustered with enteroviruses of goats and sheep. Recombination analysis showed that SD-S67 is likely to have undergone several recombination events in the process of its evolution. To the best of our knowledge, this is the first report of an enterovirus F isolate from a goat and of a coinfection with enteroviruses of different species in the same goat herd.


Author contributions

Concept and design, Xinping Wang; virus isolation, Xiaoran Chang; PCR amplification, Xu Wang and Qian Lin; analysis and interpretation, Xiaoran Chang, Junying Hu, and Menglu Cai; sample collection, Junying Hu and Xin Li, confirmation, Zecai Zhang and Weiyu Wang; drafting and editing of the manuscript, Xiaoran Chang and Xinping Wang. All authors read and approved the final manuscript.


This study was supported by the National Key Research & Development Program 2017YFD0500104 and 2016YFD0500904 and the National Natural Science Foundation of China (31572531).

Compliance with ethical standards

Conflict of interest

The authors declare that there are no conflicts of interest.

Ethical approval

The article does not contain any studies with animals performed by any of the authors.

Supplementary material

705_2019_4331_MOESM1_ESM.txt (7 kb)
Supplementary material 1 (TXT 7 kb)


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  • Xiaoran Chang
    • 1
  • Qian Lin
    • 1
  • Junying Hu
    • 1
  • Xu Wang
    • 1
  • Xin Li
    • 1
  • Menglu Cai
    • 1
  • Weiyu Wang
    • 1
  • Zecai Zhang
    • 1
  • Xinping Wang
    • 1
    • 2
    Email author
  1. 1.College of Veterinary Medicine, Key Laboratory for Zoonoses ResearchMinistry of Education, Jilin UniversityChangchunChina
  2. 2.Key Laboratory for Zoonoses ResearchMinistry of EducationChangchunChina

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