Advertisement

Archives of Virology

, Volume 164, Issue 10, pp 2537–2543 | Cite as

First detection and genetic characterization of peste des petits ruminants virus from dorcas gazelles “Gazella dorcas” in the Sudan, 2016-2017

  • Rayan M. Asil
  • Martin Ludlow
  • Abdelgadir Ballal
  • Saafass Alsarraj
  • Wegdan H. Ali
  • Baraa A. Mohamed
  • Shaza M. Mutwakil
  • Nussieba A. OsmanEmail author
Brief Report
  • 43 Downloads

Abstract

In May 2017, many free-ranging dorcas gazelles (Gazella dorcas) with suspected signs of peste des petits ruminants (PPR) were reported in Dinder National Park, South-Eastern Sudan. Peste des petits ruminants virus (PPRV) antigen and nucleic acid were detected in specimens from these gazelles using an immunocapture ELISA and a reverse transcription polymerase chain reaction (RT-PCR) assays. PPRV was also detected in four healthy semi-captive dorcas gazelles from two areas of Khartoum State. Phylogenetic analysis showed that these PPRV strains belonged to the lineage IV genotype. The present study demonstrates that gazelles are a potential wild small ruminant host for PPRV and may influence the epidemiology of PPR in the Sudan.

Notes

Acknowledgements

We are grateful to Prof. Elsayed Elowni (University of Khartoum) and Prof. Satya Parida (The Pirbright Institute, UK) for their valuable comments, the staff of the General Directorate of the Epizootics Disease Control, Khartoum, Sudan, and the Kuku Zoo (Sudan University of Science and Technology) for their kind assistance with collection of samples.

Author contributions

RMA performed most of the laboratory work and data analysis. ML helped with data interpretation and revised and finalized the manuscript. SA, WHA, BAM and SMM also contributed to these laboratory studies. AB (deceased) also contributed to the design of this study and laboratory work. NAO was responsible for the design and supervision of this research project, data analysis and interpretation, sequence and phylogenetic analysis, and wrote and finalized the drafted manuscript.

Funding

The research in this study was partially funded by a project from the Food and Agriculture Organization (FAO) (Grant No. SUD/TCP/3504) in collaboration with the Central Veterinary Research Laboratory (CVRL), Soba, Khartoum, Sudan, and by a research project for N.A. Osman from the Republic of the Sudan, Sudanese Ministry of Higher Education and Scientific Research, Commission of Scientific Research and Innovation (Grant No. 2017/972).

Compliance with ethical standards

Conflict of interest

All authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with animals performed by any of the authors.

References

  1. 1.
    Gargadennec L, Lalanne A (1942) La peste des petits ruminants. Bulletin des Services Zootechniques et des Epizooties de L’Afrique Occidental Français 5(1):16–21Google Scholar
  2. 2.
    Banyard AC, Parida S, Batten C, Oura C, Kwiatek O, Libeau G (2010) Global distribution of peste des petits ruminants virus and prospects for improved diagnosis and control. J Gen Virol 91:2885–2897CrossRefGoogle Scholar
  3. 3.
    Baron MD, Diop B, Njeumi F, Willett BJ, Bailey D (2017) Future research to underpin successful peste des petits ruminants virus (PPRV) eradication. J Gen Virol 98:2635–2644CrossRefGoogle Scholar
  4. 4.
    OIE-WAHIS (2018) Peste des petits ruminants, Bulgaria. Annual Animal Health Report, World Animal Health Information Database (WAHIS Interface)—Version 1, World Organisation for Animal Health (OIE). http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review?reportid=27029
  5. 5.
    OIE-FAO (2015) Global strategy for the control and eradication of PPR. World Organization for Animal Health (OIE); Food and Agriculture Organization of the United Nations (FAO), Contract No.: ISBN 978-92-9044-989-8; ISBN 978-92-5-108733-6. http://www.fao.org/3/a-i4460e.pdf
  6. 6.
    Maes P, Amarasinghe GK, Ayllón MA et al (2019) Taxonomy of the order Mononegavirales: second update 2018. Arch Virol 164(4):1233–1244CrossRefGoogle Scholar
  7. 7.
    Elhag Ali B (1973) A natural outbreak of rinderpest involving sheep, goats and cattle in Sudan. Bull Epizoot Dis Afr 21:421–428Google Scholar
  8. 8.
    Parida S, Muniraju M, Mahapatra M, Muthuchelvan D, Buczkowski H, Banyard AC (2015) Peste des petits ruminants. Vet Microbiol 181(1–2):90–106CrossRefGoogle Scholar
  9. 9.
    Khalafalla AI, Saeed IK, Ali YH, Abdurrahman MB, Kwiatek O, Libeau G, Obeida AA, Abbas Z (2010) An outbreak of peste des petits ruminants (PPR) in camels in the Sudan. Acta Trop 116(2):161–165CrossRefGoogle Scholar
  10. 10.
    Furley CW, Taylor WP, Obi TU (1987) An outbreak of peste des petits ruminants in a zoological collection. Vet Rec 121(19):443–447CrossRefGoogle Scholar
  11. 11.
    Aziz-ul-Rahman A, Wensman JJ, Abubakar M, Shabbir MZ, Rossiter P (2018) Peste des petits ruminants in wild ungulates. Trop Anim Health Prod 50(8):1815–1819CrossRefGoogle Scholar
  12. 12.
    Bailey D, Banyard A, Dash P, Ozkul A, Barrett T (2005) Full genome sequence of peste des petits ruminants virus, a member of the Morbillivirus genus. Virus Res 110(1–2):119–124CrossRefGoogle Scholar
  13. 13.
    Couacy-Hymann E, Roger F, Hurard C, Guillou JP, Libeau G, Diallo A (2002) Rapid and sensitive detection of peste des petits ruminants virus by a polymerase chain reaction assay. J Virol Methods 100(1–2):17–25CrossRefGoogle Scholar
  14. 14.
    Padhi A, Ma L (2014) Genetic and epidemiological insights into the emergence of peste des petits ruminants virus (PPRV) across Asia and Africa. Sci Rep 13(4):7040.  https://doi.org/10.1038/srep07040 Google Scholar
  15. 15.
    Diallo A, Taylor WP, Lefèvre PC, Provost A (1989) Atténuation d’une souche de virus de la peste des petits ruminants: candidat pour un vaccin homologue vivant. Revue d’élevage et de médecine vétérinaire des pays tropicaux 42(3):311–319Google Scholar
  16. 16.
    Tamura K, Nei M, Kumar S (2004) Prospects for inferring very large phylogenies by using the neighbor-joining method. Proc Natl Acad Sci (USA) 101:11030–11035CrossRefGoogle Scholar
  17. 17.
    Ali WH, Osman NA, Asil RM, Mohamed BA, Abdelgadir SO, Mutwakil SM, Mohamed NEB (2019) Serological Investigations of Peste des Petits Ruminants among Cattle in the Sudan. Trop Anim Health Prod 51(3):655–659CrossRefGoogle Scholar
  18. 18.
    Gür S, Albayrak H (2010) Seroprevalance of peste des petits ruminants (PPR) in goitered gazelle (Gazella subgutturosa subgutturosa) in Turkey. J Wild Dis 46(2):673–677CrossRefGoogle Scholar
  19. 19.
    Mahapatra M, Sayalel K, Muniraju M, Eblate E, Fyumagwa R, Shilinde L, Mdaki M, Keyyu J, Parida S, Kock R (2015) Spillover of peste des petits ruminants virus from domestic to wild ruminants in the Serengeti ecosystem, Tanzania. Emerg Infect Dis 21(12):2230–2234CrossRefGoogle Scholar
  20. 20.
    Sharawi SS, Yousef MR, Al-Hofufy AN, Al-Blowi MH (2010) Isolation, serological and real time PCR diagnosis of peste des petites ruminants virus in naturally exposed Arabian Gazelle in Saudi Arabia. Vet World 3(11):489–494Google Scholar
  21. 21.
    Saeed IK, Ali YH, Haj MA, Sahar MAT, Shaza MM, Baraa AM, Ishag OM, Nouri YM, Taha KM, Nada EM, Ahmed AM, Khalafalla AI, Libeau G, Diallo A (2017) Peste des petits ruminants infection in domestic ruminants in Sudan. Trop Anim Health Prod 49(4):747–754CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Pathology, Parasitology and Microbiology, College of Veterinary MedicineSudan University of Science and TechnologyKhartoum-NorthSudan
  2. 2.Virology DepartmentCentral Veterinary Research Laboratory (CVRL), SobaKhartoumSudan
  3. 3.Research Center for Emerging Infections and Zoonoses (RIZ)University of Veterinary Medicine Hannover FoundationHannoverGermany
  4. 4.Viral Vaccine Production DepartmentCentral Veterinary Research Laboratory (CVRL), SobaKhartoumSudan

Personalised recommendations