First genetic detection and characterization of canine parvovirus from diarrheic dogs in Zambia
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Although canine parvovirus (CPV) causes severe gastroenteritis in dogs globally, information on the molecular epidemiology of the virus is lacking in many African countries. Here, 32 fecal samples collected from diarrheic dogs in Zambia were tested for CPV infection using molecular assays. CPV was detected in 23 samples (71.9%). Genetic characterization revealed the predominance of CPV-2c (91.3%). This finding differs from previous reports in Africa, which indicated that CPV-2a and CPV-2b were most prevalent. Phylogenetically, most Zambian CPVs formed a distinct cluster. This is the first report on the molecular characterization of CPV in Zambia.
This work was supported by the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) and the Japan Agency for Medical Research and Development (AMED)/Japan International Cooperation Agency (JICA) within the framework of the Science and Technology Research Partnership for Sustainable Development (SATREPS).
Compliance with ethical standards
This article does not contain any studies with animals or humans performed by any of the authors.
Conflict of interest
All the authors declare that they have no competing interests.
- 17.Mwenda R, Changula K, Hang’ombe BM, Chidumayo N, Mangani AS, Kaira T, Takada A, Mweene AS, Simulundu E (2018) Characterization of field infectious bursal disease viruses in Zambia: evidence of co-circulation of multiple genotypes with predominance of very virulent strains. Avian Pathol 47:300–313CrossRefGoogle Scholar
- 21.Xie Q, Chapman MS (1996) Canine parvovirus capsid structure, analyzed at 2.9 Å resolution. J Mol Biol 264(497–520):33Google Scholar