Archives of Virology

, Volume 163, Issue 11, pp 3099–3103 | Cite as

Presence of rat bocavirus in oropharyngeal and fecal samples from murine rodents in China

  • Yi-Quan Xiong
  • Jun-Hua Zhou
  • Min-Yi Zhang
  • Fang-Fei You
  • Dong-Liang Li
  • Qing ChenEmail author
Brief Report


In this study, we detected and genetically characterized rat bocavirus (RBoV) carried in 496 murine rodents that were captured in four provinces in China between May 2015 and May 2017. RBoV-positive samples were found in all four provinces, with a total positive rate of 24.8% (123/496) in throat swabs and 58.1% (286/492) in fecal samples. Twelve nearly full-length genome sequences of RBoV were determined, and the average sequence identity was 96.2%. Phylogenetic analysis showed that RBoVs formed a distinct clade that was distinguishable from the bocaviruses discovered in humans and other animals.



We are grateful to Xue-Shan Zhong, Shao-Wei Chen, Xue-Yan Zheng, Shu-Juan Ma, Li-Na Jiang, Jin Ge, Ming Qiu, Shu-Ting Huo, Xue-Mei Ke, Wen Zhou, Xing Li, Yun Mo, Ming-Ji Cheng, Xue-Jiao Chen, Wen-Qiao He, Yu-Qi Wen and Yan-Xia Chen for their participation in collecting rodent samples.


This study was funded by National Natural Science Foundation of China (Grant no. 81373051).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This study was approved by the ethics committee of the Institutional Animal Care and Use Committee of Southern Medical University.

Supplementary material

705_2018_3943_MOESM1_ESM.docx (14 kb)
Supplementary material 1 (DOCX 14 kb)


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Epidemiology, School of Public Health, Guangdong Provincial Key Laboratory of Tropical Disease ResearchSouthern Medical UniversityGuangzhouChina
  2. 2.Department of EpidemiologyMedical College of Hunan Normal UniversityChangshaChina
  3. 3.Department of Pathogen Biology, School of Public Health, Guangdong Provincial Key Laboratory of Tropical Disease ResearchSouthern Medical UniversityGuangzhouChina

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