Advertisement

Journal of Neural Transmission

, Volume 126, Issue 9, pp 1163–1173 | Cite as

Accident patterns in trauma surgery patients with and without self-reported ADHD

  • Sarah Wolff
  • Kristin Queiser
  • Leonie Wessendorf
  • Anna Maria Meier
  • Moritz Verdenhalven
  • Oliver Grimm
  • Christoph Reimertz
  • Christoph Nau
  • Michelle Klos
  • Andreas Reif
  • Sarah Kittel-SchneiderEmail author
Psychiatry and Preclinical Psychiatric Studies - Original Article

Abstract

Attention deficit/hyperactivity disorder (ADHD) has been associated with a higher risk for accidents and injuries, leading to increased mortality. The objective of this study was to identify the types and mechanisms of accidents in a group of adult trauma victims with self-reported ADHD compared to a control group, based on Adult ADHD Self-Report Scale Version 1.1 (ASRSv1.1). A semi-open/qualitative accident questionnaire was conducted with 116 recruited patients from three trauma surgery units. The adult ADHD (aADHD) group differed significantly from the control group in self-reported psychiatric co-morbidities (p = 0.012), regular psychotropic medication use (p = 0.005), other accidents in the past year (p = 0.002), substance use before the accident (p = 0.007), and overconfidence in relation to the accident (p = 0.033). Most interestingly, we found significantly greater subjective ratings for stress (p = 0.002) and stressful/pressurising events before the accident (p = 0.026) in the adult ADHD group, as well as for self-reported stress at the time when conducting the interview (p = 0.016). The data demonstrate that special attention should be paid to interventions in stress reduction and sufficient treatment of ADHD in terms of preventing accidents and injuries in aADHD. Therefore, we suggest, in addition to pharmaceutical therapy, the integration of stress-management and coping strategies into aADHD management.

Keywords

Adult attention deficit/hyperactivity disorder (aADHD) Accidents Psychosocial stress Cross-sectional study 

Notes

Acknowledgements

The authors would like to thank all the staff members of the Occupational Accident Clinic [Berufsgenossenschaftliche Unfallklinik (BGU)] Frankfurt, the Department of Trauma, Hand and Reconstructive Surgery and Department of Oral, Dental and Cosmetic Facial surgery, University Hospital of Frankfurt as well as all patients for participation.

Funding

This study, as part of the Prevalence of Adult Attention Deficit/-Hyperactivity Disorder in Accident Victims (PrADA) study of the Department of Psychiatry, Psychosomatic Medicine and Psychotherapy at Goethe University in Frankfurt/Main, Germany, was funded by Medice Arzneimittel Pütter GmbH & Co KG. The Sponsor receives the data from the study only as cumulative, anonymized results in the form of a publication, and had no influence on study design and interpretation.

Compliance with ethical standards

Conflict of interest

AR has received speaker’s honoraria from Medice, Shire, Servier, Janssen and Neuraxpharm as well as grant support from Medice. SKS has received author’s and speaker’s honoraria as well as travel costs from Medice Arzneimittel and travel costs from Shire. All other co-authors have no conflict of interest to declare.

Ethical approval

All procedures performed in studies involving human participants were in accordance with ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendment or comparable ethical standards.

Supplementary material

702_2019_2011_MOESM1_ESM.docx (23 kb)
Supplementary material 1 (DOCX 23 kb)

References

  1. Adeyemo BO, Biederman J, Zafonte R, Kagan E, Spencer TJ, Uchida M, Kenworthy T, Spencer AE, Faraone SV (2014) Mild traumatic brain injury and ADHD. A systematic review of the literature and meta-analysis. J Atten Disord 18(7):576–584CrossRefPubMedGoogle Scholar
  2. Bachmann CJ, Philipsen A, Hoffmann F (2017) ADHD in Germany: trends in diagnosis and pharmacotherapy. Dtsch Ärzteblatt Int 114(9):141–148Google Scholar
  3. Barkley RA (2002) Major life activity and health outcomes associated with attention-deficit/hyperactivity disorder. J Clin Psychiatry 63:10–15PubMedGoogle Scholar
  4. Barkley RA, Guevremont DC, Anastopoulos AD, DuPaul GJ, Shelton TL (1993) Driving-related risks and outcomes of attention deficit hyperactivity disorder in adolescents and young adults. A 3- to 5-year follow-up survey. Pediatrics 92(2):212–218PubMedGoogle Scholar
  5. Bron TI, Bijlenga D, Breuk M, Michielsen M, Beekman ATF, Kooij JJS (2017) Risk factors for adverse driving outcomes in Dutch adults with ADHD and controls. Accid Anal Prev 111:338–344CrossRefPubMedGoogle Scholar
  6. Buchli-Kammermann J, Corbisiero S, Stieglitz R-D (2011) Screening der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) im Erwachsenenalter: Validierung der deutschen Version der ASRS-v1.1 [Screening for adult attention deficit/hyperactivity disorder (ADHD): validation of the German version of the ASRS-v1.1]. Klinische Diagnostik und Evaluation 4:219–235Google Scholar
  7. Chang Z, Lichtenstein P, D’Onofrio BM, Sjolander A, Larsson H (2014) Serious transport accidents in adults with attention-deficit/hyperactivity disorder and the effect of medication. A population-based study. JAMA Psychiatry 71(3):319–325CrossRefPubMedPubMedCentralGoogle Scholar
  8. Combs MA, Canu WH, Broman-Fulks JJ, Rocheleau CA, Nieman DC (2015) Perceived stress and ADHD symptoms in adults. J Atten Disord 19(5):425–434CrossRefPubMedGoogle Scholar
  9. Cox DJ, Madaan V, Cox BS (2011) Adult attention-deficit/hyperactivity disorder and driving. Why and how to manage it. Curr Psychiatry Rep 13(5):345–350CrossRefPubMedGoogle Scholar
  10. Curry AE, Metzger KB, Pfeiffer MR, Elliott MR, Winston FK, Power TJ (2017) Motor vehicle crash risk among adolescents and young adults with attention-deficit/hyperactivity disorder. JAMA Pediatr 171(8):756–763CrossRefPubMedPubMedCentralGoogle Scholar
  11. Dalsgaard S, Ostergaard SD, Leckman JF, Mortensen PB, Pedersen MG (2015) Mortality in children, adolescents, and adults with attention deficit hyperactivity disorder. A nationwide cohort study. Lancet (Lond, Engl) 385(9983):2190–2196CrossRefGoogle Scholar
  12. Day AJ, Brasher K, Bridger RS (2012) Accident proneness revisited: the role of psychological stress and cognitive failure. Accid Anal Prev 49:532–535CrossRefPubMedGoogle Scholar
  13. Ebert D, Krause J, Roth-Sackenheim C (2003) ADHS im Erwachsenenalter-Leitlinien auf der Basis eines Expertkonsensus mit Unterstützung der DGPPN (ADHD in adulthood—guidelines based on expert consensus with DGPPN support). Der Nervenarzt 74(10):939–946PubMedGoogle Scholar
  14. El Farouki K, Lagarde E, Orriols L, Bouvard M-P, Contrand B, Galera C (2014) The increased risk of road crashes in attention deficit hyperactivity disorder (ADHD) adult drivers. Driven by distraction? Results from a responsibility case–control study. PLoS One 9(12):e115002CrossRefPubMedPubMedCentralGoogle Scholar
  15. Faraone SV, Sergeant J, Gillberg C, Biederman J (2003) The worldwide prevalence of ADHD. Is it an American condition? World Psychiatry Off J World Psychiatr Assoc 2(2):104–113Google Scholar
  16. Faraone SV, Asherson P, Banaschewski T, Biederman J, Buitelaar JK, Ramos-Quiroga JA, Rohde LA, Sonuga-Barke EJS, Tannock R, Franke B (2015) Attention-deficit/hyperactivity disorder. Nat Rev Dis Prim 1:15020CrossRefPubMedGoogle Scholar
  17. Fayyad J, Sampson NA, Hwang I, Adamowski T, Aguilar-Gaxiola S, Al-Hamzawi A, Andrade LHSG, Borges G, de Girolamo G, Florescu S, Gureje O, Haro JM, Hu C, Karam EG, Lee S, Navarro-Mateu F, O’Neill S, Pennell B-E, Piazza M, Posada-Villa J, ten Have M, Torres Y, Xavier M, Zaslavsky AM, Kessler RC (2017) The descriptive epidemiology of DSM-IV Adult ADHD in the World Health Organization World Mental Health Surveys. Atten Deficit Hyperact Disord 9(1):47–65CrossRefGoogle Scholar
  18. Gardner RM, Yengo-Kahn A, Bonfield CM, Solomon GS (2017) Comparison of baseline and post-concussion ImPACT test scores in young athletes with stimulant-treated and untreated ADHD. Physician Sportsmed 45(1):1–10CrossRefGoogle Scholar
  19. Groom MJ, van Loon E, Daley D, Chapman P, Hollis C (2015) Driving behaviour in adults with attention deficit/hyperactivity disorder. BMC Psychiatry 15:1–11CrossRefGoogle Scholar
  20. Groß-Lesch S, Dempfle A, Reichert S, Jans T, Geissler J, Kittel-Schneider S, Nguyen TT, Reif A, Lesch K-P, Jacob CP (2016) Sex- and subtype-related differences in the comorbidity of adult ADHDs. J Atten Disord 20(10):855–866CrossRefPubMedGoogle Scholar
  21. Hirvikoski T, Lindholm T, Nordenström A, Nordström A-L, Lajic S (2009) High self-perceived stress and many stressors, but normal diurnal cortisol rhythm, in adults with ADHD (attention-deficit/hyperactivity disorder). Horm Behav 55(3):418–424CrossRefPubMedGoogle Scholar
  22. Ilie G, Vingilis ER, Mann RE, Hamilton H, Toplak M, Adlaf EM, Kolla N, Ialomiteanu A, van der Mass M, Asbridge M, Vingilis-Jaremko L, Rehm J, Cusimano MD (2015) The association between traumatic brain injury and ADHD in a Canadian adult sample. J Psychiatr Res 69:174–179CrossRefPubMedGoogle Scholar
  23. Jaber L, Kirsh D, Diamond G, Shuper A (2015) Long-term functional outcomes in israeli adults diagnosed in childhood with attention deficit hyperactivity disorder. Isr Med Assoc J 17(8):481–485PubMedGoogle Scholar
  24. Jerome L, Segal A, Habinski L (2006) What we know about ADHD and driving risk: a literature review, meta-analysis and critique. J Can Acad Child Adolesc Psychiatry 15(3):105–125PubMedPubMedCentralGoogle Scholar
  25. Kessler RC, Adler L, Ames M, Demler O, Faraone S, Hiripi E, Howes MJ, Jin R, Secnik K, Spencer T, Ustun TB, Walters EE (2005) The World Health Organization Adult ADHD Self-Report Scale (ASRS). A short screening scale for use in the general population. Psychol Med 35(2):245–256CrossRefPubMedGoogle Scholar
  26. Kessler RC, Adler L, Barkley R, Biederman J, Conners CK, Demler O, Faraone SV, Greenhill LL, Howes MJ, Secnik K, Spencer T, Ustun TB, Walters EE, Zaslavsky AM (2006) The prevalence and correlates of adult ADHD in the United States. Results from the National Comorbidity Survey Replication. Am J Psychiatry 163(4):716–723CrossRefPubMedPubMedCentralGoogle Scholar
  27. Kittel-Schneider S, Spiegel S, Renner T, Romanos M, Reif A, Reichert S, Heupel J, Schnetzler L, Stopper H, Jacob C (2016) Cytogenetic effects of chronic methylphenidate treatment and chronic social stress in adults with attention-deficit/hyperactivity disorder. Pharmacopsychiatry 49(4):146–154CrossRefPubMedGoogle Scholar
  28. Koisaari T, Michelsson K, Holopainen JM, Maksimainen R, Paivansalo J, Rantala K, Tervo T (2015) Traffic and criminal behavior of adults with attention deficit-hyperactivity with a prospective follow-up from birth to the age of 40 years. Traffic Inj Prev 16(8):824–830CrossRefPubMedGoogle Scholar
  29. Komurcu E, Bilgic A, Herguner S (2014) Relationship between extremity fractures and attention-deficit/hyperactivity disorder symptomatology in adults. Int J Psychiatry Med 47(1):55–63CrossRefPubMedGoogle Scholar
  30. Kooij SJJ, Bejerot S, Blackwell A, Caci H, Casas-Brugué M, Carpentier PJ, Edvinsson D, Fayyad J, Foeken K, Fitzgerald M, Gaillac V, Ginsberg Y, Henry C, Krause J, Lensing MB, Manor I, Niederhofer H, Nunes-Filipe C, Ohlmeier MD, Oswald P, Pallanti S, Pehlivanidis A, Ramos-Quiroga JA, Rastam M, Ryffel-Rawak D, Stes S, Asherson P (2010) European consensus statement on diagnosis and treatment of adult ADHD. The European Network Adult ADHD. BMC Psychiatry 10:67CrossRefPubMedPubMedCentralGoogle Scholar
  31. Lackschewitz H, Hüther G, Kröner-Herwig B (2008) Physiological and psychological stress responses in adults with attention-deficit/hyperactivity disorder (ADHD). Psychoneuroendocrinology 33(5):612–624CrossRefPubMedGoogle Scholar
  32. London AS, Landes SD (2016) Attention deficit hyperactivity disorder and adult mortality. Prev Med 90:8–10CrossRefPubMedGoogle Scholar
  33. McEwen BS, Sapolsky RM (1995) Stress and cognitive function. Curr Opin Neurobiol 5(2):205–216CrossRefPubMedGoogle Scholar
  34. Merrill RM, Lyon JL, Baker RK, Gren LH (2009) Attention deficit hyperactivity disorder and increased risk of injury. Adv Med Sci 54(1):20–26CrossRefPubMedGoogle Scholar
  35. Merrill RM, Thygerson SM, Palmer CA (2016) Risk of injury according to attention deficit hyperactivity disorder, comorbid mental illness, and medication therapy. Pharmacopsychiatry 49(2):45–50CrossRefPubMedGoogle Scholar
  36. Mörstedt B, Corbisiero S, Stieglitz R-D (2016) Normierung der Adult ADHD Self-Report-Scale-V1.1 und der ADHS Selbstbeurteilungsskala an einer repräsentativen deutschsprachigen Stichprobe. Diagnostica 62(4):199–211CrossRefGoogle Scholar
  37. Murphy KR, Barkley RA, Bush T (2002) Young adults with attention deficit hyperactivity disorder. Subtype differences in comorbidity, educational, and clinical history. J Nerv Ment Dis 190(3):147–157CrossRefPubMedGoogle Scholar
  38. Nogueira M, Bosch R, Valero S, Gomez-Barros N, Palomar G, Richarte V, Corrales M, Nasillo V, Vidal R, Casas M, Ramos-Quiroga JA (2014) Early-age clinical and developmental features associated to substance use disorders in attention-deficit/hyperactivity disorder in adults. Compr Psychiatry 55(3):639–649CrossRefPubMedGoogle Scholar
  39. Ohman L, Nordin S, Bergdahl J, Slunga Birgander L, Stigsdotter Neely A (2007) Cognitive function in outpatients with perceived chronic stress. Scand J Work Environ Health 33(3):223–232CrossRefPubMedGoogle Scholar
  40. Pani SC, Hillis H, Chaballout T, Al Enazi W, AlAttar Y, Aboramadan M (2014) Knowledge and attitude of Saudi teachers of students with attention-deficit hyperactivity disorder towards traumatic dental injuries. Dent Traumatol Off Publ Int Assoc Dent Traumatol 30(3):222–226CrossRefGoogle Scholar
  41. Quinlan EB, Cattrell A, Jia T, Artiges E, Banaschewski T, Barker G, Bokde ALW, Bromberg U, Büchel C, Brühl R, Conrod PJ, Desrivieres S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Martinot J-L, Paillère Martinot M-L, Nees F, Papadopoulos-Orfanos D, Paus T, Poustka L, Smolka MN, Vetter NC, Walter H, Whelan R, Glennon JC, Buitelaar JK, Happé F, Loth E, Barker ED, Schumann G (2017) Psychosocial stress and brain function in adolescent psychopathology. Am J Psychiatry 174(8):785–794CrossRefPubMedGoogle Scholar
  42. Ramos Olazagasti MA, Klein RG, Mannuzza S, Belsky ER, Hutchison JA, Lashua-Shriftman EC, Castellanos FX (2013) Does childhood attention-deficit/hyperactivity disorder predict risk-taking and medical illnesses in adulthood? J Am Acad Child Adolesc Psychiatry 52(2):153–162CrossRefPubMedGoogle Scholar
  43. Raz S, Leykin D (2015) Psychological and cortisol reactivity to experimentally induced stress in adults with ADHD. Psychoneuroendocrinology 60:7–17CrossRefPubMedGoogle Scholar
  44. Reimer B, D’Ambrosio LA, Gilbert J, Coughlin JF, Biederman J, Surman C, Fried R, Aleardi M (2005) Behavior differences in drivers with attention deficit hyperactivity disorder. The driving behavior questionnaire. Accid Anal Prev 37(6):996–1004CrossRefPubMedGoogle Scholar
  45. Sabuncuoglu O (2007) Traumatic dental injuries and attention-deficit/hyperactivity disorder. Is there a link? Dent Traumatol Off Publ Int Assoc Dent Traumatol 23(3):137–142CrossRefGoogle Scholar
  46. Sargant NN, Finley F (2013) Le TDAH au volant: conseils aux adolescents. TDAH en pratique 5(4):13–15Google Scholar
  47. Schlander M, Trott G-E, Schwarz O (2010a) Gesundheitsökonomie der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung in Deutschland Teil 1. Versorgungsepidemiologie und Krankheitskosten (The health economics of attention deficit hyperactivity disorder in Germany. Part 1: Health care utilization and cost of illness). Der Nervenarzt 81(3):289–300CrossRefPubMedGoogle Scholar
  48. Schlander M, Trott G-E, Schwarz O (2010b) Gesundheitsökonomie der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung in Deutschland. Teil 2. Therapeutische Optionen und ihre Kosteneffektivität (The health economics of attention deficit hyperactivity disorder in Germany. Part 2: Therapeutic options and their cost-effectiveness). Der Nervenarzt 81(3):301–314CrossRefPubMedGoogle Scholar
  49. Scott SB, Graham-Engeland JE, Engeland CG, Smyth JM, Almeida DM, Katz MJ, Lipton RB, Mogle JA, Munoz E, Ram N, Sliwinski MJ (2015) The effects of stress on cognitive aging, physiology and emotion (ESCAPE) project. BMC Psychiatry 15:146CrossRefPubMedPubMedCentralGoogle Scholar
  50. Simon N, Rolland B, Karila L (2015) Methylphenidate in adults with attention deficit hyperactivity disorder and substance use disorders. Curr Pharm Des 21(23):3359–3366CrossRefPubMedGoogle Scholar
  51. Sobanski E (2006) Psychiatric comorbidity in adults with attention-deficit/hyperactivity disorder (ADHD). Eur Arch Psychiatry Clin Neurosci 256(Suppl 1):i26–i31CrossRefPubMedGoogle Scholar
  52. Sobanski E, Sabljic D, Alm B, Skopp G, Kettler N, Mattern R, Strohbeck-Kuhner P (2008) Driving-related risks and impact of methylphenidate treatment on driving in adults with attention-deficit/hyperactivity disorder (ADHD). J Neural Transm (Vienna, Austria: 1996) 115(2):347–356CrossRefGoogle Scholar
  53. Swensen A, Birnbaum HG, Ben Hamadi R, Greenberg P, Cremieux P-Y, Secnik K (2004) Incidence and costs of accidents among attention-deficit/hyperactivity disorder patients. J Adolesc Health Off Publ Soc Adolesc Med 35(2):346.e1–346.e9Google Scholar
  54. Turel O, Bechara A (2016) Social networking site use while driving. ADHD and the mediating roles of stress, self-esteem and craving. Front Psychol 7:455PubMedPubMedCentralGoogle Scholar
  55. Vaa T (2014) ADHD and relative risk of accidents in road traffic. A meta-analysis. Accid Anal Prev 62:415–425CrossRefPubMedGoogle Scholar
  56. Vingilis E, Mann RE, Erickson P, Toplak M, Kolla NJ, Seeley J, Jain U (2014) Attention deficit hyperactivity disorder, other mental health problems, substance use, and driving. Examination of a population-based, representative Canadian sample. Traffic Inj Prev 15(sup1):S1–S9CrossRefPubMedGoogle Scholar
  57. White RD, Harris GD, Gibson ME (2014) Attention deficit hyperactivity disorder and athletes. Sports Health 6(2):149–156CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  • Sarah Wolff
    • 1
  • Kristin Queiser
    • 1
  • Leonie Wessendorf
    • 1
  • Anna Maria Meier
    • 1
  • Moritz Verdenhalven
    • 1
  • Oliver Grimm
    • 1
  • Christoph Reimertz
    • 2
  • Christoph Nau
    • 3
  • Michelle Klos
    • 4
  • Andreas Reif
    • 1
  • Sarah Kittel-Schneider
    • 1
    Email author
  1. 1.Department of Psychiatry, Psychosomatic Medicine and PsychotherapyUniversity Hospital Frankfurt, Goethe UniversityFrankfurt am MainGermany
  2. 2.Occupational Accident Clinic Frankfurt (Berufsgenossenschaftliche Unfallklinik, BGU)Frankfurt am MainGermany
  3. 3.Department of Trauma, Hand and Reconstructive SurgeryUniversity Hospital Frankfurt, Goethe UniversityFrankfurt am MainGermany
  4. 4.Department of Oral, Maxillofacial and Plastic Facial SurgeryUniversity Hospital Frankfurt, Goethe UniversityFrankfurt am MainGermany

Personalised recommendations