Spontaneous regression of a clival chordoma. Case report

  • Evan D. Bander
  • Gary Kocharian
  • Benjamin Liechty
  • Apostolos J. Tsiouris
  • Theodore H. SchwartzEmail author
Case Report - Brain Tumors
Part of the following topical collections:
  1. Brain tumors


In this case report, we present a rare and previously unreported case of spontaneous regression of a histologically consistent clival chordoma. At the time of diagnosis, imaging demonstrated a T2 hyperintense and T1 isointense midline skull base mass, centered in the nasopharynx, with scalloping of the ventral clivus consistent with a chordoma measuring 3.1 × 1.9 × 3.0 cm (8.84 cm3). On pre-operative imaging 2 months later, with no intervening therapy, the mass had regressed by 61.7% to a size of 2.3 × 2.1 × 1.4 cm (3.38 cm3). The patient self-administered several herbal supplements and animal oils which may have contributed to tumor regression. The purpose of this report is to document this rare occurrence and provide a comprehensive description of the case details and list of the various medications, herbs, and supplements used prior to this rare event.


Chordoma Spontaneous Regression 


Compliance with ethical standards

The patient has consented to the submission of the case report for publication.


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  • Evan D. Bander
    • 1
  • Gary Kocharian
    • 1
  • Benjamin Liechty
    • 2
  • Apostolos J. Tsiouris
    • 3
  • Theodore H. Schwartz
    • 1
    Email author
  1. 1.Department of NeurosurgeryWeill Cornell Medicine, New York Presbyterian HospitalNew YorkUSA
  2. 2.Department of PathologyWeill Cornell Medicine, New York Presbyterian HospitalNew YorkUSA
  3. 3.Department of RadiologyWeill Cornell Medicine, New York Presbyterian HospitalNew YorkUSA

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