Efficiency and complications of Woven EndoBridge (WEB) devices for treatment of larger, complex intracranial aneurysms—a single-center experience
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Several recently published multicenter studies have reported high treatment feasibility, high safety, and good 6-month to 1-year efficiency when treating smaller intracranial aneurysms (IA) with WEB deployment. The purpose of the study was to evaluate the long-term efficiency and complications related to WEB treatment of larger, complex intracranial aneurysms in a small single-center cohort.
Patients with ruptured and unruptured IA were treated with WEB devices; data were collected prospectively and analyzed retrospectively. The study evaluates complications and clinical and radiological findings at immediate and last available follow-up.
The study included 16 patients with 16 aneurysms and a median follow-up time of 36 months, range 13–49 months; 9/16 were females. Median age 59 with range 39–71 years. Mean aneurysm size 11.3 ± 1.7 mm, predominant location at the basilar artery bifurcation and anterior communicating artery. Three out of sixteen IAs were ruptured. Even though 75% of the IAs were immediately occluded completely, retreatment was eventually necessary in 7/15 (46.7%). Increasing neck remnants and recurrences were mainly observed past 1-year follow-up. The WEB device showed modifications over time, with six devices showing signs of compression in the long term. There was one fatality due to aneurysm rupture after 4 years.
The long-term efficiency of WEB deployment in larger, complex aneurysms is low with about half of the cases needing at least one retreatment. A large fraction of WEB collapse past 1-year follow-up.
KeywordsWEB Endovascular treatment Intracranial aneurysms
Woven Endoluminal Bridge
WEB dual layer device
WEB single layer device
WEB single layer spherical device
First segment of the anterior cerebral artery
Posterior communicating artery
Computed tomography angiography
Magnetic resonance angiography
Magnetic resonance imaging
Anterior communicating artery
Middle cerebral artery
Vertebral artery dissection
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.
(The study has been approved by the institutional data protection officer as a quality study with reference number 2017/993)
Informed consent was waived by the data protection officer for this type of study.
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