Acta Neurochirurgica

, Volume 161, Issue 1, pp 15–15 | Cite as

Intracranial foreign material granuloma after neurosurgical procedures

  • Shadi Al-AfifEmail author
  • Joachim K. Krauss
Letter to the Editor (by Invitation) - Brain Tumors
Part of the following topical collections:
  1. Brain tumors

Dear Editor,

We appreciate the interest of Drs. Akhaddar and Turgut in our recent manuscript published in this journal [2]. Since acceptance of our manuscript, they have communicated a systematic review on foreign body granulomas following cranial surgery in World Neurosurgery [1]. We wish to congratulate them for their thoughtful and comprehensive analysis. It is important to attract the attention to this thus far largely neglected but clinically significant issue.

In our manuscript, we concentrated on foreign body granulomas after foreign body material was left intentionally (except Tefloma [3]). As Drs. Akhaddar and Turgut point out, the problem of a material left “unintentionally” is most likely underreported and we assume there is an unknown dark figure [4].

We agree with the authors that a diagnosis of intracranial foreign body granuloma can definitely be made only after histopathological examination. In addition, however, a detailed history and clinical examination are necessary to make a correct decision in the management of such entities (surgery vs. wait and see).

Neurosurgeons must be aware of the occurrence of foreign body granuloma. In particular, it becomes evident that this is a well treatable condition with usually good outcome.


  1. 1.
    Akhaddar A, Turgut AT, Turgut M (2018) Foreign body granuloma following cranial surgery: a systematic review of published cases. World Neurosurg.
  2. 2.
    Al-Afif S, Hatipoglu Majernik G, Hermann EJ, Esmaeilzadeh M, Hartmann C, Krauss JK (2018) Intracranial foreign material granulomas after cranial surgery. Acta Neurochir 160(11):2069–2075CrossRefGoogle Scholar
  3. 3.
    Capelle H-H, Brandis A, Tschan CA, Krauss JK (2010) Treatment of recurrent trigeminal neuralgia due to Teflon granuloma. J Headache Pain 11(4):339–344CrossRefGoogle Scholar
  4. 4.
    Peloquin P, Vannemreddy PSSV, Watkins LM, Byrne RW (2012) Intracranial cotton ball gossypiboma mimicking recurrent meningioma: report of a case with literature review for intentional and unintentional foreign body granulomas. Clin Neurol Neurosurg 114(7):1039–1041CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Austria, ein Teil von Springer Nature 2018
corrected publication 2018

Authors and Affiliations

  1. 1.Department of NeurosurgeryHannover Medical SchoolHanoverGermany

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