Acta Neurochirurgica

, Volume 161, Issue 3, pp 509–515 | Cite as

Synchronous bilateral hemifacial spasm: case-report and literature review

  • Tao Huang
  • Nan-xiang XiongEmail author
  • Peng Fu
  • Ahmed Abdelmaksoud
  • Lei Wang
  • Hong-yang Zhao
Case Report - Functional Neurosurgery - Movement disorders
Part of the following topical collections:
  1. Functional Neurosurgery – Movement disorders


Bilateral hemifacial spasm (biHFS) is an infrequent cranial nerve disorder that causes patients to suffer from severe psychological stress, and there are no reported cases of synchronous biHFS. In this study, a 46-year-old right-handed woman was diagnosed with a synchronous biHFS. After one unilateral microvascular decompression (MVD) surgery, the left facial twitching movements relieved immediately, and the right side twitching movements self-relieved the next day. Although there was a delayed hemorrhage, the patient achieved a satisfactory outcome defined as cessation of the twitching movements without recurrence. Based on the present case and related literature, we speculate that anatomical connections between bilateral facial nuclei and hyperactivity of facial nuclei play important roles in the biHFS, and they may, at least in some cases, be the decisive factors regarding the origin, development, and relief of the consequent contralateral spasm.


Synchronous Bilateral Hemifacial spasm Facial nucleus Mechanism 



Hemifacial spasm


Bilateral hemifacial spasm


Microvascular decompression


Root exit zone


Magnetic resonance imaging




Anterior inferior cerebellar artery


Positron emission tomography


Facial nucleus


Trigeminal nucleus


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from the participant included in the study.


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Neurosurgery, Union Hospital, Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

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