Can patients with symptomatic Tarlov cysts be differentiated from patients with specific low back pain based on comprehensive history taking?
- 348 Downloads
Tarlov cysts (TCs) are expanded nerve root sheaths that occur near the dorsal root ganglion and result from increased intraspinal hydrostatic pressure. TCs most frequently affect the lumbosacral plexus and therefore may cause specific symptoms such as perineal pain and neurogenic bladder, bowel, and sphincter problems. It has been estimated that 1% of the population has symptomatic Tarlov cysts (STCs). However, STCs appear to be underdiagnosed, with the pain reported by patients commonly attributed to degenerative alterations seen on MRI. The aim of the present study is to investigate the utility of a comprehensive questionnaire for use by physicians in establishing the diagnosis of STCs.
We compared questionnaire responses regarding patient history between 33 patients diagnosed with symptomatic TCs and 42 patients with chronic low back pain and sciatica due to disc problems or degenerative or inflammatory disorders. The diagnosis of STCs was confirmed using nerve conduction studies (NCS) and electromyography (EMG) of the sacral myotomes by an expert neurophysiologist.
The questionnaire responses revealed specific differences in perineal symptoms (perineal pain, dyspareunia, coccygodynia), bowel symptoms (constipation, diarrhea), bladder symptoms (hesitation, retention, frequency), and anal sphincter problems (anal pain, mild fecal incontinence). Additionally, sitting, walking, and straining aggravated pain more frequently in STC patients, and STC patients were more often forced to stop working and/or reduce their social activities.
Including the above-listed items in the patient history might facilitate differentiation of low back pain and sciatica due to STCs from that due to disc problems or degenerative or inflammatory disorders.
KeywordsTarlov cysts Perineal pain Non-specific low back pain Ischialgia
We thank Debbie West and Frank Feigenbaum for permission to use their International Tarlov Cyst Questionnaire (Feigenbaum Neurosurgery PA, Dallas, TX and Cyprus). We also thank Anouchka Laenen for statistical assistance.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
For this type of study, formal consent is not required.
- 4.Feigenbaum F, Henderson F (2012) Tarlov cysts. In: Benzel E (ed) Spine surgery, vol. 2. Elsevier, Philadelphia, pp 1135–1140Google Scholar
- 7.Hulens M, Bruyninckx F, Somers A, Stalmans I, Peersman B, Vansant G, Rasschaert R, De Mulder P, Dankaerts W (2017) Electromyography and a review of the literature provide insights into the role of sacral perineural cysts in unexplained chronic pelvic, perineal and leg pain syndromes. Int J Phys Med Rehabil 5:1000407–1000401. https://doi.org/10.4172/2329-9096.1000407 Google Scholar
- 9.Jiang W, Qiu Q, Hao J, Zhang X, Shui W, Hu Z (2015) Percutaneous fibrin gel injection under C-arm fluoroscopy guidance: a new minimally invasive choice for symptomatic sacral perineural cysts. PLoS One 10:e0118254. https://doi.org/10.1371/journal.pone.0118254 CrossRefPubMedPubMedCentralGoogle Scholar
- 21.Sun JJ, Wang ZY, Teo M, Li ZD, Wu HB, Yen RY, Zheng M, Chang Q, Yisha Liu I (2013) Comparative outcomes of the two types of sacral extradural spinal meningeal cysts using different operation methods: a prospective clinical study. PLoS One 8:e83964. https://doi.org/10.1371/journal.pone.0083964 CrossRefPubMedPubMedCentralGoogle Scholar