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Microchimica Acta

, 187:113 | Cite as

A graphite pencil electrode with electrodeposited Pt-CuO for nonenzymatic amperometric sensing of glucose over a wide linear response range

  • Anjali Sreekumar
  • Punnakkal Navaneeth
  • Punathil Vasu Suneesh
  • Bipin G Nair
  • T. G. Satheesh BabuEmail author
Original Paper

Abstract

A disposable nonenzymatic glucose sensor was obtained by pulsed electrodeposition of Pt-CuO on a graphite pencil electrode (GPE). The morphology of the modified GPE was studied using SEM, and the chemical composition of the coating was examined by EDAX and XRD. The electrochemical response of the modified GPE was compared with individual copper- and platinum-modified GPEs. The electrodeposition parameters were optimized with respect to the electrocatalytic activity of the deposits towards glucose oxidation. Best operated at a working potential of 0.6 V vs. Ag/AgCl, the sensor has a sensitivity of 2035 μA mM−1 cm−2, a 0.1 μM detection limit and a wide linear response range that extends up to 25 mM. It is highly selective for glucose in the presence of various exogenous and endogenous interfering species. Eventhough the requirement of alkaline medium for sensing is a limitation, easy fabrication procedure, very high sensitivity and selectivity, wide analytical range, and disposable sensor characteristics show potential application towards blood glucose determination.

Graphical abstract

Schematic representation of the Pt-CuO electrodeposited pencil graphite electrode for the nonenzymatic determination of glucose.

Keywords

Graphite pencil electrode Pulsed electrodeposition Chronopotentiometry Pt-CuO nanomaterials Bi-metalic catalyst Direct electrochemical oxidation Blood glucose 

Notes

Acknowledgements

Authors gratefully acknowledge the Department of Biotechnology (DBT), Government of India for the financial support (Sanction Nos. BT/PR15018/MED/32/447/2015 and BT/PR4076/MED/32/221/2011).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.

Supplementary material

604_2019_4077_MOESM1_ESM.docx (252 kb)
ESM 1 (DOCX 252 kb)

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2020

Authors and Affiliations

  • Anjali Sreekumar
    • 1
    • 2
  • Punnakkal Navaneeth
    • 1
    • 2
  • Punathil Vasu Suneesh
    • 1
    • 2
  • Bipin G Nair
    • 3
  • T. G. Satheesh Babu
    • 1
    • 2
    Email author
  1. 1.Amrita Biosensor Research LabAmrita School of Engineering Coimbatore, Amrita Vishwa VidyapeethamTamil NaduIndia
  2. 2.Department of SciencesAmrita School of Engineering Coimbatore, Amrita Vishwa VidyapeethamTamil NaduIndia
  3. 3.Amrita School of Biotechnology, Amritapuri, Amrita Vishwa VidyapeethamTamil NaduIndia

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