Electrochemical sensing of L-ascorbic acid by using a glassy carbon electrode modified with a molybdophosphate film
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Electrochemical sensing of L-ascorbic acid (AA) is reported based on the use of a redox-active molybdophosphate film on a glassy carbon electrode (GCE). Molybdophosphate is formed by reacting hydroxyapatite nanoparticles with sodium molybdate. The modified GCE can be utilized for detection of AA, typically at a working potential of 0.4 V (vs. Ag/AgCl). The GCE has a decreased overpotential and enhanced sensitivity (219 μA·mM−1·cm−2). Response is linear in the 1 μM to 1.5 mM AA concentration range, and the limit of detection is 4 nM. The selectivity of this sensor makes it a useful tool for accurate determination of AA in practical samples as shown for a vitamin C tablet and for spiked beverages.
KeywordsHydroxyapatite nanoparticles L-Ascorbic acid Molybdate Molybdophosphate film
The authors thank the support of this work by the National Natural Science Foundation of China (No. 21575165).
Compliance with ethical standards
The author(s) declare that they have no competing interests.
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