Microchimica Acta

, 186:103 | Cite as

A spherical metal-organic coordination polymer for the microextraction of neonicotinoid insecticides prior to their determination by HPLC

  • Hui Ding
  • Rongyu Wang
  • Wei Liu
  • Supan Cheng
  • Wenhua JiEmail author
  • Zhenjia Zheng
  • Xiao WangEmail author
Original Paper


The authors describe a new spherical metal-organic coordination polymer (MOCP) for use as an adsorbent in solid-phase microextraction (SPME). By applying the ions Co(II), Fe(II), Cu(II), and Zn(II) in these polymers, MOCP with different morphology were obtained. The respective coatings for SPME display different extraction efficiency towards neonicotinoid insecticides (neo-nics). The Co(II)@MOCP coating displays an improved extraction capability for neo-nics when compared to the four commercially available coatings studied. Following extraction with the Co(II)@MOCP-coated fiber, the neo-nics were eluted using 1 mL of trifluoroacetic acid/acetonitrile solution and quantified by high performance liquid chromatography. The method, when applied to spiked honey samples, has good linearity (0.5–600 μg kg−1) and a low limit of detection (0.05–0.15 μg kg−1). The precision (n = 6) for a single fiber was in the range of 3.6–8.3%. The reproducibility (for n = 5) from fiber-to-fiber ranges between 5.4 and 8.8%. The Co(II)@MOCP-coated fiber can be reused more than 80 times without any apparent reduction in its performance. In addition, the relative recoveries from spiked honey samples are very good (91.5%–103.5%).

Graphical abstract

A spherical metal-organic coordination polymer (MOCP) was synthesized under the regulation of Co(II) and used for the solid-phase microextraction (SPME) of neonicotinoid insecticides found in honey.


Solid-phase microextraction Co(BF4)2 Neonicotinoid pesticides High performance liquid chromatography Honey samples 



This work was supported by Shandong Agricultural Applied Technology Innovation Project (2018) and the Funds of Shandong “Double Tops” Program.

Compliance with ethical standards

The author(s) declare that they have no competing interests.

Supplementary material

604_2018_3210_MOESM1_ESM.docx (1.2 mb)
ESM 1 (DOCX 1316 kb)


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Shandong Key Laboratory of TCM Quality Control Technology, Shandong Analysis and Test CenterQilu University of Technology (Shandong Academy of Sciences)JinanChina
  2. 2.School of PharmacyShandong University of Traditional Chinese MedicineJinanChina
  3. 3.College of Food Science and Engineering, Key Laboratory of Food Processing Technology and Quality Control in Shandong ProvinceShandong Agricultural UniversityTaianChina

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