An amino-modified metal-organic framework (type UiO-66-NH2) loaded with cadmium(II) and lead(II) ions for simultaneous electrochemical immunosensing of triazophos and thiacloprid
- 172 Downloads
A method is described for simultaneous voltammetric determination of the pesticides triazophos (TRS) and thiacloprid (THD). A glassy carbon electrode (GCE) was modified with a metal-organic framework (type UiO-66-NH2) which has a large specific surface (1018 m2·g−1) and contains large amounts of Cd(II) and Pb(II) ions, with adsorption capacities of 230 and 271 mg·g−1, respectively. The antigen-loaded particles were then bound to antibody, magnetically separated, and analyzed by square wave voltammetry to give signals for Cd(II) and Pb(II) at −0.82 and − 0.56 V (vs. Ag/AgCl) for TRS and THD, respectively. Under optimized conditions, the method has a wide linear range (0.2–750 ng·mL−1) and low detection limits (0.07 and 0.1 ng·mL−1 at a S/N of 3 for TRS and THD, respectively). It is perceived that this assay represents a useful tool for simultaneous determination of multiple pesticide residues. The method has a wide scope in that may be extended to monitoring of other small organic pollutants by changing the types of metal ions and by using other antibodies.
KeywordsMOF UiO-66-NH2 Simultaneous voltammetric determination Electrochemical immunosensing Multiple pesticide residues Square wave voltammetry Cd(II) ion Pb(II) ion
This work was supported financially by the Experimental Technology Research Project of Zhejiang University (No. SJS201710) and the National Key Research and Development Program of China (2016YFD0200804, 2017YFF0210200, 2017YFD0201805).
Compliance with ethical standards
The author(s) declare that they have no competing interest.
- 1.Li L, Zhou S, Jin L, Zhang C, Liu W (2010) Enantiomeric separation of organophosphorus pesticides by high-performance liquid chromatography, gas chromatography and capillary electrophoresis and their applications to environmental fate and toxicity assays. J Chromatogr B 878(17–18):1264–1276CrossRefGoogle Scholar
- 2.Lara-Ortega FJ, Robles-Molina J, Brandt S, Schutz A, Gilbert-Lopez B, Molina-Diaz A, Garcia-Reyes JF, Franzke J (2018) Use of dielectric barrier discharge ionization to minimize matrix effects and expand coverage in pesticide residue analysis by liquid chromatography-mass spectrometry. Anal Chim Acta 1020:76–85CrossRefGoogle Scholar
- 3.Haraga T, Ouchi K, Sato Y, Hoshino H, Tanaka R, Fujihara T, Kurokawa H, Shibukawa M, Ishimori KI, Kameo Y, Saito S (2018) Safe and rapid development of capillary electrophoresis for ultratrace uranyl ions in radioactive samples by way of fluorescent probe selection for actinide ions from a chemical library. Anal Chim Acta 1032:188–196CrossRefGoogle Scholar
- 10.Dridi F, Marrakchi M, Gargouri M, Saulnier J, Jaffrezic-Renault N, Lagarde F (2017) Nanomaterial-based electrochemical biosensors for food safety and quality assessment. Nanobiosensors 167–204Google Scholar
- 25.Abid HR, Ang HM, Wang S (2012) Effects of ammonium hydroxide on the structure and gas adsorption of nanosized Zr-MOFs (UiO-66). Nanoscale 4(10):3089–3094Google Scholar
- 30.Du P, Jin M, Chen G, Zhang C, Cui X, Zhang Y, Zhang Y, Zou P, Jiang Z, Cao X (2017) Competitive colorimetric triazophos immunoassay employing magnetic microspheres and multi-labeled gold nanoparticles along with enzymatic signal enhancement. Microchim Acta 184(99):1–8Google Scholar