Microchimica Acta

, 185:245 | Cite as

A nanoporous palladium(II) bridged coordination polymer acting as a peroxidase mimic in a method for visual detection of glucose in tear and saliva

  • Vinita
  • Narsingh R. Nirala
  • Madhu Tiwari
  • Rajiv Prakash
Original Paper
  • 72 Downloads

Abstract

A nanoporous coordination polymer (NPCP) was prepared from palladium(II) chloride and 4-amino-3-hydrazino-5-mercapto-1,2,4-triazole and is shown to act as a peroxidase mimetic. It can catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by H2O2 which is formed on enzymatic oxidation of glucose by glucose oxidase. Based on these findings, a sensitive glucose test was worked out at 652 nm where the intensity if the greenish-blue product is related to the actual concentration of glucose. Figures of merit include (a) rather low Km value (30 μM) which evidences the strong binding affinity of the NPCP toward glucose, (b) a high v(max) (8.5 M·s−1), (c) a 47 nM detection limit, (d) a lifetime of a month, (e) a wide working pH range (2–10), and (f) a 25–80 °C temperature range. The assay was applied to non-invasive determination of glucose assay in tear, saliva where the detection limits are found to be 61 and 91 nM, respectively.

Graphical abstract

DSchematic of the mechanism of the peroxidase like catalytic activity of AHMT-Pd NPCP that was applied in a selective colorimetric method for glucose detection based on TMB oxidation in the presence of enzymatically generated H2O2.

Keywords

AHMT–Pd NPCP Glucose TMB Peroxidase Colorimetry Portable test kit 

Notes

Acknowledgments

Ms. Vinita and Dr. Narsingh R. Nirala are greatly acknowledged to the CSIR, JRF (File no- 09/013(0641)/2016-EMR-I) and SERB N-PDF (PDF/2016/000243) respectively for fellowship. Authors are also thankful to CIF, IIT (BHU) Varanasi for providing instrumentation facility. Vinita, NR Nirala and M Tiwari are responsible for all the experiments and data. All the authoths have contributed in manuscript writing.

Compliance with ethical standards

The author(s) declare that they have no competing interests.

Supplementary material

604_2018_2776_MOESM1_ESM.doc (6.2 mb)
ESM 1 (DOC 6347 kb)

References

  1. 1.
    Long Pan †, Michelle B. Sander †, Xiaoying Huang †, et al (2004) Microporous metal organic materials: promising candidates as sorbents for hydrogen storage. J Am Chem Soc 126 (5):1308–1309. doi:  https://doi.org/10.1021/JA0392871 CrossRefGoogle Scholar
  2. 2.
    Tiwari M, Kumar A, Prakash R (2016) Nano-porous network of DMTD-Ag coordination polymer for the ultra trace detection of anticholinergic drug. Polymer (Guildf) 82:66–74.  https://doi.org/10.1016/j.polymer.2015.11.017 CrossRefGoogle Scholar
  3. 3.
    Akhbari K, Morsali A (2013) Modulating methane storage in anionic nano-porous MOF materials via post-synthetic cation exchange process. Dalton Trans 42:4786–4789.  https://doi.org/10.1039/c3dt32846e CrossRefGoogle Scholar
  4. 4.
    Cheng J-K, Zhang J, Yin P-X, Lin QP, Li ZJ, Yao YG (2009) Temperature-controlled syntheses of substituted 1,2,4-Triazolelead(II) complexes: active lone pair and N−H···X (X = cl, Br, I) hydrogen bonds. Inorg Chem 48:9992–9994.  https://doi.org/10.1021/ic901653y CrossRefGoogle Scholar
  5. 5.
    Haedler AT, Kreger K, Issac A, Wittmann B, Kivala M, Hammer N, Köhler J, Schmidt HW, Hildner R (2015) Long-range energy transport in single supramolecular nanofibres at room temperature. Nature 523:196–199.  https://doi.org/10.1038/nature14570 CrossRefGoogle Scholar
  6. 6.
    Li B, Wen H-M, Cui Y, Zhou W, Qian G, Chen B (2016) Emerging multifunctional metal-organic framework materials. Adv Mater 28:8819–8860.  https://doi.org/10.1002/adma.201601133 CrossRefGoogle Scholar
  7. 7.
    Kuwamura N, Kurioka Y, Konno T (2017) A platinum(ii)–palladium(ii)–nickel( ii ) heterotrimetallic coordination polymer showing a cooperative effect on catalytic hydrogen evolution. Chem Commun 53:846–849.  https://doi.org/10.1039/C6CC08789B CrossRefGoogle Scholar
  8. 8.
    Nirala NR, Khandelwal G, Kumar B, Vinita, Prakash R , Kumar V (2017) One step electro-oxidative preparation of graphene quantum dots from wood charcoal as a peroxidase mimetic. Talanta 173:36–43. doi:  https://doi.org/10.1016/J.TALANTA.2017.05.061, 2017
  9. 9.
    Vinita NNR, Prakash R (2018) One step synthesis of AuNPs@MoS2-QDs composite as a robust peroxidase- mimetic for instant unaided eye detection of glucose in serum, saliva and tear. Sensors Actuators B Chem 263:109–119.  https://doi.org/10.1016/J.SNB.2018.02.085 CrossRefGoogle Scholar
  10. 10.
    Li Z, Sheng L, Meng A, Xie C, Zhao K (2016) A glassy carbon electrode modified with a composite consisting of reduced graphene oxide, zinc oxide and silver nanoparticles in a chitosan matrix for studying the direct electron transfer of glucose oxidase and for enzymatic sensing of glucose. Microchim Acta 183:1625–1632.  https://doi.org/10.1007/s00604-016-1791-x CrossRefGoogle Scholar
  11. 11.
    Dayakar T, Venkateswara Rao K, Bikshalu K, Rajendar V, Si-HyunPark (2017) Novel synthesis and structural analysis of zinc oxide nanoparticles for the non enzymatic glucose biosensor. Mater Sci Eng C 75:1472–1479.  https://doi.org/10.1016/J.MSEC.2017.02.032 CrossRefGoogle Scholar
  12. 12.
    Ellis WC, Tran CT, Denardo MA, Fischer A, Ryabov AD, Collins TJ (2009) Design of more powerful iron-TAML peroxidase enzyme mimics. J Am Chem Soc 131:18052–18053.  https://doi.org/10.1021/ja9086837 CrossRefGoogle Scholar
  13. 13.
    Nirala NR, Abraham S, Kumar V, Bansal A, Srivastava A, Saxena PS (2015) Colorimetric detection of cholesterol based on highly efficient peroxidase mimetic activity of graphene quantum dots. Sensors Actuators B Chem 218:42–50.  https://doi.org/10.1016/j.snb.2015.04.091 CrossRefGoogle Scholar
  14. 14.
    Dhara K, Mahapatra DR (2018) Electrochemical nonenzymatic sensing of glucose using advanced nanomaterials. Microchim Acta 185:49.  https://doi.org/10.1007/s00604-017-2609-1 CrossRefGoogle Scholar
  15. 15.
    Nasir M, Nawaz MH, Latif U, Yaqub M, Hayat A, Rahim A (2017) An overview on enzyme-mimicking nanomaterials for use in electrochemical and optical assays. Microchim Acta 184:323–342.  https://doi.org/10.1007/s00604-016-2036-8 CrossRefGoogle Scholar
  16. 16.
    Wu X, Ge J, Yang C, Hou M, Liu Z (2015) Facile synthesis of multiple enzyme-containing metal–organic frameworks in a biomolecule-friendly environment. Chem Commun 51:13408–13411.  https://doi.org/10.1039/C5CC05136C CrossRefGoogle Scholar
  17. 17.
    Li Z, Zhang Y, Su Y, Ouyang P, Ge J, Liu Z (2014) Spatial co-localization of multi-enzymes by inorganic nanocrystal–protein complexes. Chem Commun 50:12465–12468.  https://doi.org/10.1039/C4CC05478D CrossRefGoogle Scholar
  18. 18.
    Ortiz-Gómez I, Salinas-Castillo A, García AG, Álvarez-Bermejo JA, de Orbe-Payá I, Rodríguez-Diéguez A, Capitán-Vallvey LF (2018) Microfluidic paper-based device for colorimetric determination of glucose based on a metal-organic framework acting as peroxidase mimetic. Microchim Acta 185:47.  https://doi.org/10.1007/s00604-017-2575-7 CrossRefGoogle Scholar
  19. 19.
    Chen J, Chen Q, Chen J, Qiu H (2016) Magnetic carbon nitride nanocomposites as enhanced peroxidase mimetics for use in colorimetric bioassays, and their application to the determination of H2O2 and glucose. Microchim Acta 183:3191–3199.  https://doi.org/10.1007/s00604-016-1972-7 CrossRefGoogle Scholar
  20. 20.
    Huang L, Zhu W, Zhang W, Chen K, Wang J, Wang R, Yang Q, Hu N, Suo Y, Wang J (2018) Layered vanadium(IV) disulfide nanosheets as a peroxidase-like nanozyme for colorimetric detection of glucose. Microchim Acta 185:7.  https://doi.org/10.1007/s00604-017-2552-1 CrossRefGoogle Scholar
  21. 21.
    Wang K, Wang H, Wang R et al (2013) Palygorskite hybridized carbon nanocomposite as a high-performance Electrocatalyst support for formic acid oxidation. South African J Chem 66:86–91Google Scholar
  22. 22.
    Daems N, Sheng X, Vankelecom IFJ, Pescarmona PP (2014) Metal-free doped carbon materials as electrocatalysts for the oxygen reduction reaction. J Mater Chem A 2:4085–4110.  https://doi.org/10.1039/C3TA14043A CrossRefGoogle Scholar
  23. 23.
    Lv M, Mei T, Zhang C et al (2014) Selective and sensitive electrochemical detection of dopamine based on water-soluble porphyrin functionalized graphene nanocomposites. RSC Adv 4:9261.  https://doi.org/10.1039/c3ra47234e CrossRefGoogle Scholar
  24. 24.
    Kaya İ, Erçağ A, Avcı A, Çulhaoğlu S (2014) Synthesis, characterization and conductivity properties of novel oligomer Schiff bases derived from 4-Amino-3-hydrazino-5-mercapto-1, 2, 4-triazole and their reactions with VO(IV), cu(II) ions. J Inorg Organomet Polym Mater 24:665–675.  https://doi.org/10.1007/s10904-014-0036-x CrossRefGoogle Scholar
  25. 25.
    Broido A (1969) A simple, sensitive graphical method of treating thermogravimetric analysis data. J Polym Sci Part A-2 Polym Phys 7:1761–1773.  https://doi.org/10.1002/pol.1969.160071012 CrossRefGoogle Scholar
  26. 26.
    Wood PM (1988) The potential diagram for oxygen at pH 7. Biochem J 253:287–289CrossRefGoogle Scholar
  27. 27.
    Liu Q, Ding Y, Yang Y, Zhang L, Sun L, Chen P, Gao C (2016) Enhanced peroxidase-like activity of porphyrin functionalized ceria nanorods for sensitive and selective colorimetric detection of glucose. Mater Sci Eng C 59:445–453.  https://doi.org/10.1016/J.MSEC.2015.10.046 CrossRefGoogle Scholar
  28. 28.
    Lin T, Zhong L, Song Z, Guo L, Wu H, Guo Q, Chen Y, Fu FF, Chen G (2014) Visual detection of blood glucose based on peroxidase-like activity of WS2 nanosheets. Biosens Bioelectron 62:302–307.  https://doi.org/10.1016/j.bios.2014.07.001 CrossRefGoogle Scholar
  29. 29.
    Xu Y, Schoonen MAA (2000) The absolute energy positions of conduction and valence bands of selected semiconducting minerals. Am Mineral 85:543–556.  https://doi.org/10.2138/am-2000-0416 CrossRefGoogle Scholar
  30. 30.
    Su L, Feng J, Zhou X, Ren C, Li H, Chen X (2012) Colorimetric detection of urine glucose based ZnFe2O 4 magnetic nanoparticles. Anal Chem 84:5753–5758.  https://doi.org/10.1021/ac300939z CrossRefGoogle Scholar
  31. 31.
    Wang N, Sun J, Chen L, Fan H, Ai S (2015) A Cu2(OH)3Cl-CeO2 nanocomposite with peroxidase-like activity, and its application to the determination of hydrogen peroxide, glucose and cholesterol. Microchim Acta 182:1733–1738.  https://doi.org/10.1007/s00604-015-1506-8 CrossRefGoogle Scholar
  32. 32.
    Ding C, Yan Y, Xiang D, Zhang C, Xian Y (2016) Magnetic Fe3S4 nanoparticles with peroxidase-like activity, and their use in a photometric enzymatic glucose assay. Microchim Acta 183:625–631.  https://doi.org/10.1007/s00604-015-1690-6 CrossRefGoogle Scholar
  33. 33.
    Choleva TG, Gatselou VA, Tsogas GZ, Giokas DL (2018) Intrinsic peroxidase-like activity of rhodium nanoparticles, and their application to the colorimetric determination of hydrogen peroxide and glucose. Microchim Acta 185:22.  https://doi.org/10.1007/s00604-017-2582-8 CrossRefGoogle Scholar
  34. 34.
    Liu C, Sheng Y, Sun Y, Feng J, Wang S, Zhang J, Xu J, Jiang D (2015) A glucose oxidase-coupled DNAzyme sensor for glucose detection in tears and saliva. Biosens Bioelectron 70:455–461.  https://doi.org/10.1016/j.bios.2015.03.070 CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  1. 1.School of Materials Science and TechnologyIndian Institute of Technology (Banaras Hindu University)VaranasiIndia

Personalised recommendations