A glassy carbon electrode modified with N-doped carbon dots for improved detection of hydrogen peroxide and paracetamol
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Nitrogen doped carbon dots (NCDs) were synthesized using a low temperature approach and used to modify a glassy carbon electrode (GCE) via dipping. The oxygen groups on the surface of the NCDs, and the charge delocalization of the NCDs warrant an excellent electrocatalytic activity of the GCE toward oxidation of paracetamol (PA) and reduction of H2O2. PA and H2O2 were detected at 0.34 V and −0.4 V (both vs. Ag/AgCl) using differential pulse voltammetry and amperometric I-T measurement, respectively. The modified GCE has a linear response to PA in the 0.5 to 600 μM concentration range, and to H2O2 in the 0.05 μM to 2.25 mM concentration range. The detection limits are 157 nM and 41 nM, respectively. In our perception, the modified GCE holds promise for stable, selective and sensitive determination of PA and H2O2 in pharmaceutical analysis.
KeywordsLow temperature synthesis Surface functional group Electrode modification Cyclic voltammetry Differential pulse voltammetry Pharmaceutical analysis H2O2 disinfector Electrochemical sensor Nanomaterial
This work has been financially supported by Research Foundation from Hangzhou Dianzi University (KYS205617071) and Zhejiang Province Natural Science Foundation of China (LQ18E010001).
Compliance with ethical standards
The author(s) declare that they have no competing interests.
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