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Microchimica Acta

, 185:87 | Cite as

A glassy carbon electrode modified with N-doped carbon dots for improved detection of hydrogen peroxide and paracetamol

  • Li FuEmail author
  • Aiwu Wang
  • Guosong Lai
  • Cheng-Te Lin
  • Jinhong Yu
  • Aimin Yu
  • Zhong Liu
  • Kefeng Xie
  • Weitao SuEmail author
Original Paper

Abstract

Nitrogen doped carbon dots (NCDs) were synthesized using a low temperature approach and used to modify a glassy carbon electrode (GCE) via dipping. The oxygen groups on the surface of the NCDs, and the charge delocalization of the NCDs warrant an excellent electrocatalytic activity of the GCE toward oxidation of paracetamol (PA) and reduction of H2O2. PA and H2O2 were detected at 0.34 V and −0.4 V (both vs. Ag/AgCl) using differential pulse voltammetry and amperometric I-T measurement, respectively. The modified GCE has a linear response to PA in the 0.5 to 600 μM concentration range, and to H2O2 in the 0.05 μM to 2.25 mM concentration range. The detection limits are 157 nM and 41 nM, respectively. In our perception, the modified GCE holds promise for stable, selective and sensitive determination of PA and H2O2 in pharmaceutical analysis.

Graphic abstract

Nitrogen doped carbon dots (NCDs) were synthesized and used to modify a glassy carbon electrode. Surface functional groups on NCDs can trigger electrocatalytic reactions toward paracetamol oxidation and H2O2 reduction with high sensitivities.

Keywords

Low temperature synthesis Surface functional group Electrode modification Cyclic voltammetry Differential pulse voltammetry Pharmaceutical analysis H2O2 disinfector Electrochemical sensor Nanomaterial 

Notes

Acknowledgements

This work has been financially supported by Research Foundation from Hangzhou Dianzi University (KYS205617071) and Zhejiang Province Natural Science Foundation of China (LQ18E010001).

Compliance with ethical standards

The author(s) declare that they have no competing interests.

Supplementary material

604_2017_2646_MOESM1_ESM.docx (261 kb)
ESM 1 (DOCX 261 kb)

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • Li Fu
    • 1
    Email author
  • Aiwu Wang
    • 2
  • Guosong Lai
    • 3
  • Cheng-Te Lin
    • 4
  • Jinhong Yu
    • 4
  • Aimin Yu
    • 3
    • 5
  • Zhong Liu
    • 6
  • Kefeng Xie
    • 7
  • Weitao Su
    • 1
    Email author
  1. 1.College of Materials and Environmental EngineeringHangzhou Dianzi UniversityHangzhouPeople’s Republic of China
  2. 2.Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials ScienceCity University of Hong KongHong KongHong Kong
  3. 3.Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis & Reuse Technology, Department of ChemistryHubei Normal UniversityHuangshiPeople’s Republic of China
  4. 4.Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingboChina
  5. 5.Department of Chemistry and Biotechnology, Faculty of Science, Engineering and TechnologySwinburne University of TechnologyHawthornAustralia
  6. 6.Key Laboratory of Comprehensive and Highly Efficient Utilization of Salt Resources, Qinghai Institute of Salt LakesChinese Academy of SciencesXiningPeople’s Republic of China
  7. 7.State Key Laboratory of Plateau Ecology and AgricultureQinghai UniversityXiningPeople’s Republic of China

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