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Laparoscopic surgery in patients diagnosed with clinical N2 colon cancer

  • Masakatsu NumataEmail author
  • Sho Sawazaki
  • Toru Aoyama
  • Hiroshi Tamagawa
  • Teni Godai
  • Tsutomu Sato
  • Hiroyuki Saeki
  • Yusuke Saigusa
  • Masataka Taguri
  • Hiroyuki Mushiake
  • Takashi Oshima
  • Norio Yukawa
  • Manabu Shiozawa
  • Munetaka Masuda
  • Yasushi Rino
Original Article
  • 11 Downloads

Abstract

Purpose

The benefits of laparoscopic surgery for colorectal cancer have been well established. Several randomized controlled trials have demonstrated similar oncological outcomes between laparoscopic and open surgery for colon cancer. However, whether or not laparoscopic surgery is acceptable in patients with clinical N2 colon cancer is unclear. Therefore, the present study aimed to evaluate the safety and oncological outcomes of laparoscopic surgery for clinical N2 colon cancer.

Methods

This retrospective study assessed a prospective database and identified 262 consecutive patients with clinical N2 colon cancer who underwent either laparoscopic or open primary resection between 2000 and 2016. After propensity-score matching, 162 patients were analyzed. The primary outcome of interest was the 3-year recurrence-free survival rate, and the secondary outcome of interest was the postoperative complication rate.

Results

The 3-year recurrence-free survival rate did not differ markedly between the laparoscopic and open surgery groups (77.4% vs. 76.5%, p = 0.620). In addition, the incidence of postoperative complications did not differ markedly between the laparoscopic and open surgery groups (16.6% vs. 24.0%, p = 0.317).

Conclusions

Our findings suggest that laparoscopic surgery is safe and effective for clinical N2 colon cancer. Laparoscopic resection can be considered in patients diagnosed with clinical N2 colon cancer.

Keywords

Colon cancer Laparoscopic resection Long-term outcomes N2 Clinical N2 

Notes

Funding

None declared.

Compliance with ethical standards

Conflict of interest

Drs. Masakatsu Numata, Sho Sawazaki, Toru Aoyama, Hiroshi Tamagawa, Tsutomu Sato, Hiroyuki Saeki, Yusuke Saigusa, Masataka Taguri, Hiroyuki Mushiake, Takashi Oshima, Norio Yukawa, Manabu Shiozawa, Munetaka Masuda, and Yasushi Rino have no conflicts of interest or financial ties to disclose.

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Masakatsu Numata
    • 1
    Email author
  • Sho Sawazaki
    • 1
  • Toru Aoyama
    • 1
  • Hiroshi Tamagawa
    • 1
  • Teni Godai
    • 2
  • Tsutomu Sato
    • 1
  • Hiroyuki Saeki
    • 3
  • Yusuke Saigusa
    • 4
  • Masataka Taguri
    • 4
  • Hiroyuki Mushiake
    • 1
  • Takashi Oshima
    • 5
  • Norio Yukawa
    • 1
  • Manabu Shiozawa
    • 5
  • Munetaka Masuda
    • 1
  • Yasushi Rino
    • 1
  1. 1.Department of SurgeryYokohama City UniversityYokohamaJapan
  2. 2.Department of SurgeryFujisawa Shounandai HospitalFujisawaJapan
  3. 3.Department of SurgeryYokohama Minami Kyosai HospitalYokohamaJapan
  4. 4.Department of BiostatisticsYokohama City UniversityYokohamaJapan
  5. 5.Department of Gastroenterological SurgeryKanagawa Cancer HospitalYokohamaJapan

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