Acta Diabetologica

, Volume 55, Issue 9, pp 987–988 | Cite as

Reply to Dereke, J., Hillman, M. “The significance of biomarkers such as FABP4 in gestational diabetes mellitus and the importance of rigorous peer review” Acta Diabetol (2017) 54:885.

  • Hui Ning
  • Hong Tao
  • Zhanping Weng
  • Xingbo ZhaoEmail author
Letter to the Editor

Dear Editor,

We thank the Editor and Dereke and Hillman [1] for raising several important issues particularly concerning the “Materials and methods” section that were overlooked in compiling our manuscript published in Acta Diabetologica [2].

Indeed, we found that the statistical analysis section contained several mistakes, for which we deeply apologize. We immediately analyzed all of our data in the manuscript again, using appropriate statistical tools, and found that the new statistical results remain correct. Therefore, the conclusion of our manuscript is also valid. We appreciate the opportunity for us to clarify the above issues, point-by-point, as follows.

First of all, the authors state that ANOVA has been performed for multiple comparisons despite the fact that ANOVA has not been used in the study.

Response: we apologize for the mistake in describing the statistical method used. The data were first analyzed by Kolmogorov–Smirnov test to determine the distribution of data....


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Standard

This article does not contain any studies with human or animal subjects performed by any of the authors.

Informed consent

For this type of study, formal consent is not required.


  1. 1.
    Dereke J, Hillman M (2017) The significance of biomarkers such as FABP4 in gestational diabetes mellitus and the importance of rigorous peer review. Acta Diabetol 54(9):885–886. CrossRefPubMedGoogle Scholar
  2. 2.
    Ning H et al (2016) Plasma fatty acid-binding protein 4 (FABP4) as a novel biomarker to predict gestational diabetes mellitus. Acta Diabetol 53(6):891–898CrossRefPubMedGoogle Scholar
  3. 3.
    Kralisch S et al (2009) Serum levels of adipocyte fatty acid binding protein are increased in gestational diabetes mellitus. Eur J Endocrinol 160(1):33–38CrossRefPubMedGoogle Scholar
  4. 4.
    Ortega-Senovilla H et al (2011) Gestational diabetes mellitus causes changes in the concentrations of adipocyte fatty acid-binding protein and other adipocytokines in cord blood. Diabetes Care 34(9):2061–2066CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Li YY et al (2015) Increased plasma levels of FABP4 and PTEN is associated with more severe insulin resistance in women with gestational diabetes mellitus. Med Sci Monit 21:426–431CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  • Hui Ning
    • 1
    • 2
  • Hong Tao
    • 2
  • Zhanping Weng
    • 2
  • Xingbo Zhao
    • 1
    Email author
  1. 1.Department of Obstetrics and GynaecologyShandong Provincial Hospital Affiliated to Shandong UniversityJinanChina
  2. 2.Department of Obstetrics and GynaecologyQingdao Municipal HospitalQingdaoChina

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