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Evaluation of the serum fructosamine concentrations in transition period and its relationship with serum proteins and energy characteristics in dairy cows

  • Morteza Hasanabadi
  • Mehrdad MohriEmail author
  • Hesam A. Seifi
  • Mohammad Heidarpour
Original Article
  • 6 Downloads

Abstract

The relationship between fructosamine (FRUC) and glucose (GLU) amounts in dog was previously reported. On the other hand, no correlations were reported in transition dairy cow and late-pregnant sheep. Similar controversy also existed concerning the relationship between FRUC, albumin (ALB), and total protein (TP) concentrations. Thirty-three healthy Holstein cows were enrolled in to the study. Blood samples were obtained by jugular venipuncture at 3 and 1 weeks before and 1 and 3 weeks after calving. The concentrations of FRUC, GLU, ALB, TP, β hydroxybutyrate (BHBA), and non-esterified fatty acids (NEFA) were measured with automated biochemical analyzer, using commercial kits. SPSS software, version 20 (SPSS Inc., Chicago, USA) was used for data analysis. The mean ± SE of fructosamine for all cows during the study was 355.6 ± 4.5 μmol/l. There was significant difference in the serum concentration of FRUC post-partum, and throughout of trial, but not at pre-partum period. The maximum concentration of FRUC was at W−1 and decreased thereafter. There were significant positive correlations between FRUC and GLU concentrations at pre-partum, post-partum, and overall time of the study. There were significant negative correlations between FRUC and NEFA concentrations at pre-partum, post-partum, and overall time of the study. There were no correlations between FRUC, TP, ALB, and BHBA amounts at pre-partum, post-partum, and overall time of the study. Linear regression analysis between each sampling amount of GLU and three consecutive FRUC concentrations did not reveal significant correlation between GLU and FRUC. According to present results, fructosamine measurement could be considered as a useful indicator of energy economy in transition period.

Keywords

Albumin Fructosamine Transition period Energy characteristics Serum protein 

Notes

Funding information

This work was supported by Ferdowsi University of Mashhad, grant number 3/18174.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The protocol of study was confirmed by animal welfare committee of Ferdowsi University of Mashhad (18174/3) in accordance with institutional and national and/or international guidelines.

References

  1. Cantley CE, Ford DM, Heath MF (1991) Serum fructosamine in ovine pregnancy toxemia: a possible prognostic index. Vet Rec 128:525–526CrossRefGoogle Scholar
  2. Coppo JA (2001) Evolution of fructosaminaemia and glucaemia during the growth of unweaned and early weaned half-bred zebu calves. Vet Res Commun 25:449–459CrossRefGoogle Scholar
  3. Coppo JA, Mussart de coppo NB (1997) La glicosilacion de proteinas hematicas como evaluacion retrospective de la glucemia. Aplicaciones en medicina veterinaria. Rev Med Vet 78:292–295Google Scholar
  4. Denis AE, Richard WN, Claudia ER (1999) Comparison of serum fructosamine and blood glycosylated hemoglobin concentration for assessment of glycemic control in cats with diabetes mellitus. J Am Vet Med Assoc 1999(214):1794–1798Google Scholar
  5. Eckersal PD (2008) Proteins, proteomics, and dysproteinemias. In: Kaneko JJ, Harvey JW, Bruss ML (eds) Clinical biochemistry of domestic animals, 6th edn. Academic, San Diego, pp 117–155CrossRefGoogle Scholar
  6. Filipović N, Stojević Z, Prvanović N (2010) Serum fructosamine concentrations in relation to metabolic changes during late pregnancy and early lactation in mares. Berl Munch Tierarztl Wochenschr 123:116–173Google Scholar
  7. Filipović N, Stojević Z, Masek T, Mikulec Z, Prvanović N (2011) Relationship between fructosamine with serum protein, albumin and glucose concentrations in dairy ewes. Small Rum Res 96:46–48CrossRefGoogle Scholar
  8. Jensen AL, Petersen MB, Houe H (1993) Determination of fructosamine concentration in bovine serum samples. J Vet Med Assoc 40:111–117CrossRefGoogle Scholar
  9. Kaneko JJ (2008) Carbohydrate metabolism and its diseases. In: Kaneko JJ, Harvey JW, Bruss ML (eds) Clinical biochemistry of domestic animals, 6th edn. Academic, San Diego, pp 45–80CrossRefGoogle Scholar
  10. Kawamoto M, Kaneko JJ, Heusner AA, Feldman EC (1992) Koizumi I) Relation of fructosamine to serum protein, albumin and glucose concentrations in healthy and diabetic dogs. Am J Vet Res 53:851–855Google Scholar
  11. Loste A, Marca MC (1999) Study of the effect of total serum protein and albumin concentrations on canine fructosamine concentration. Can J Vet Res 63:138–141Google Scholar
  12. Loste A, Marca MC, Perez M, Unzueta A (2001) Clinical value of fructosamine measurements in non-healthy dogs. Vet Res Commun 25:109–115CrossRefGoogle Scholar
  13. Megahed AA, Hiew MWH, Constable PD (2018) Clinical utility of plasma fructosamine concentration as a hypoglycemic biomarker during early lactation in dairy cattle. J Vet Intern Med 32:846–852CrossRefGoogle Scholar
  14. Mostafavi M, Seifi HA, Mohri M, Jamshidi A (2015) Evaluation of fructosamine as a new biomarker for diagnosis of hepatic lipidosis in dairy cows. Anim Prod Sci 55:1005–1010CrossRefGoogle Scholar
  15. Pourmohammad R, Mohri M, Seifi HA (2018) Relationship between fructosamine and glucose, total protein, and albumin concentrations of serum in late pregnancy and early lactation of dairy Saanen goat. Iranian J Vet Sci Tech 10:27–32Google Scholar
  16. Radostits OM, Clive CG, Kenneth WH, Constable PD (2007) Veterinary medicine: a text book of the diseases of cattle, horses, sheep, pigs and goats, 10th edn. Saundres Ltd., PhiladelphiaGoogle Scholar
  17. Ropstad E (1987) Serum fructosamine levels in dairy cows related to metabolic status in early lactation. Acta Vet Scand 28(3–4):291–298Google Scholar
  18. Sorondo ML, Cirio A (2009) Evaluation of the serum fructosamine test to monitor plasma glucose concentration in the transition dairy cow. J Dairy Res 76:173–178CrossRefGoogle Scholar
  19. Sorondo ML, Cirio A (2011) Evaluation of the serum ructosamine test to monitor plasma Glu concentration in the late-pregnant sheep. Anim Prod Sci 51:662–666CrossRefGoogle Scholar
  20. Thoresen SI, Bredal WP (1998) An evaluation of serum fructosamine as a marker of the duration of hypoproteinaemic conditions in dogs. Vet Res Commun 22:167–177CrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Ltd., part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Clinical Sciences, School of Veterinary MedicineFerdowsi University of MashhadMashhadIran
  2. 2.Department of Clinical Sciences and Center of Excellence in Ruminant Abortion and Neonatal Mortality, School of Veterinary MedicineFerdowsi University of MashhadMashhadIran

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