Spiritual well-being mediates the association between attachment insecurity and psychological distress in advanced cancer patients
- 224 Downloads
Abstract
Purpose
The diagnosis of a terminal disease bears existential challenges, which activate the attachment system. Attachment insecurity, as well as existential resources, such as spiritual well-being, influences patients’ extent of psychological distress. Knowledge about the interrelation of these constructs is limited. Based on current research, we assume spiritual well-being to mediate the association of attachment insecurity and psychological distress.
Methods
We obtained data from the baseline measurement of a randomized controlled trial in advanced cancer patients. Patients were sampled from the University Medical Centers of Hamburg and Leipzig, Germany. Main outcome measures included the Patient Health Questionnaire (PHQ-9), the Death and Dying Distress Scale (DADDS), the Functional Assessment of Chronic Illness Therapy–Spiritual Well-Being Scale (FACIT-Sp), and the Experience in Close Relationships Scale (ECR-M16) for assessing attachment insecurity. We tested the mediation hypothesis with two regression analyses using bootstrapping procedure.
Results
A total of 190 patients were included. Spiritual well-being mediated the association of attachment insecurity and depression (R2 = 11%), as well as death anxiety (R2 = 15%), in fearful-avoidant attached patients. Neither dismissingly nor preoccupied attached patients differ in terms of spiritual well-being and psychological distress in comparison with secure attached patients.
Conclusion
Spiritual well-being plays a relevant role in advanced cancer patient’s mental health through mediating the association of attachment and psychological distress. Developing a better understanding of the interdependency of the constructs of spiritual well-being and attachment can help to develop individually tailored advanced cancer care programs and psychotherapeutic interventions.
Trial registration
NCT02051660
Keywords
Advanced cancer Attachment Spiritual well-being Depression Death anxietyNotes
Compliance with ethical standards
The study protocol was approved by local ethics committees in both study centers (Hamburg reference number: PV4435; Leipzig reference number: 143–14–14042014). All patients provided written informed consent prior to participation and could withdraw their informed consent at all times without having any disadvantage in their medical or psychological treatment
Conflict of interest
This research was supported by the German Cancer Aid. The authors declare not having any financial relationship with the organization. The authors have full control of all primary data and agree to allow the journal to review the data if requested.
References
- 1.Kissane DW (2012) The relief of existential suffering. Arch Intern Med 172(19):1501–1505. https://doi.org/10.1001/archinternmed.2012.3633 CrossRefPubMedGoogle Scholar
- 2.Bowlby J (1977) The making and breaking of affectional bonds. I. Aetiology and psychopathology in the light of attachment theory. An expanded version of the fiftieth Maudsley lecture, delivered before the Royal College of Psychiatrists, 19 November 1976. Br J Psychiatry 130(3):201–210. https://doi.org/10.1192/bjp.130.3.201 CrossRefPubMedGoogle Scholar
- 3.Nicholls W, Hulbert-Williams N, Bramwell R (2014) The role of relationship attachment in psychological adjustment to cancer in patients and caregivers: a systematic review of the literature. Psycho-Oncology 23(10):1083–1095. https://doi.org/10.1002/pon.3664 CrossRefPubMedGoogle Scholar
- 4.Scheffold K, Philipp R, Koranyi S, Engelmann D, Schulz-Kindermann F, Härter M, Mehnert A (2018) Insecure attachment predicts depression and death anxiety in advanced cancer patients. Palliat Support Care 16(3):308–316. https://doi.org/10.1017/S1478951517000281 CrossRefPubMedGoogle Scholar
- 5.Ciechanowski P, Sullivan M, Jensen M, Romano J, Summers H (2003) The relationship of attachment style to depression, catastrophizing and health care utilization in patients with chronic pain. Pain 104(3):627–637. https://doi.org/10.1016/S0304-3959(03)00120-9 CrossRefPubMedGoogle Scholar
- 6.Hunter JJ, Maunder RG (2001) Using attachment theory to understand illness behavior. Gen Hosp Psychiatry 23(4):177–182. https://doi.org/10.1016/S0163-8343(01)00141-4 CrossRefPubMedGoogle Scholar
- 7.Brennan KA, Clark CL, Shaver PR (1998) Self-report measurement of adult attachment: an integrative overview. In: Simpson JA, Rholes WS (eds) Attachment theory and close relationships. Guilford Press, New York, pp 46–76Google Scholar
- 8.Bartholomew K, Horowitz LM (1991) Attachment styles among young adults: a test of a four-category model. J Pers Soc Psychol 61(2):226–244CrossRefGoogle Scholar
- 9.Peteet JR, Balboni MJ (2013) Spirituality and religion in oncology. CA Cancer J Clin 63(4):280–289. https://doi.org/10.3322/caac.21187 CrossRefPubMedGoogle Scholar
- 10.Vehling S, Lehmann C, Oechsle K, Bokemeyer C, Krüll A, Koch U, Mehnert A (2011) Global meaning and meaning-related life attitudes: exploring their role in predicting depression, anxiety, and demoralization in cancer patients. Support Care Cancer 19(4):513–520. https://doi.org/10.1007/s00520-010-0845-6 CrossRefPubMedGoogle Scholar
- 11.Scheffold K, Mehnert A, Müller V, Koch U, Härter M, Vehling S (2014) Sources of meaning in cancer patients - influences on global meaning, anxiety and depression in a longitudinal study. Eur J Cancer Care (Engl) 23(4):472–480. https://doi.org/10.1111/ecc.12152 CrossRefGoogle Scholar
- 12.Canada AL, Murphy PE, Fitchett G, Peterman AH, Schover LR (2008) A 3-factor model for the FACIT-Sp. Psycho-Oncology 17(9):908–916. https://doi.org/10.1002/pon.1307 CrossRefPubMedGoogle Scholar
- 13.Lo C, Zimmermann C, Gagliese L, Li M, Rodin G (2011) Sources of spiritual well-being in advanced cancer. BMJ Support Palliat Care 1(2):149–153. https://doi.org/10.1136/bmjspcare-2011-000005 CrossRefPubMedGoogle Scholar
- 14.Sherman AC, Merluzzi TV, Pustejovsky JE, Park CL, George L, Fitchett G, Jim HSL, Munoz AR, Danhauer SC, Snyder MA, Salsman JM (2015) A meta-analytic review of religious or spiritual involvement and social health among cancer patients. Cancer 121(21):3779–3788. https://doi.org/10.1002/cncr.29352 CrossRefPubMedPubMedCentralGoogle Scholar
- 15.Loetz C, Müller J, Frick E, Petersen Y, Hvidt NC, Mauer C (2013) Attachment theory and spirituality: two threads converging in palliative care? Evid Based Complement Alternat Med 2013:740291. https://doi.org/10.1155/2013/740291 CrossRefPubMedPubMedCentralGoogle Scholar
- 16.Hiebler-Ragger M, Falthansl-Scheinecker J, Birnhuber G, Fink A, Unterrainer HF (2016) Facets of spirituality diminish the positive relationship between insecure attachment and mood pathology in young adults. PLoS One 11(6):e0158069. https://doi.org/10.1371/journal.pone.0158069 CrossRefPubMedPubMedCentralGoogle Scholar
- 17.Lo C, Hales S, Rydall A et al (2015) Managing Cancer And Living Meaningfully: study protocol for a randomized controlled trial. Trials 16:391. https://doi.org/10.1186/s13063-015-0811-1 CrossRefPubMedPubMedCentralGoogle Scholar
- 18.Scheffold K, Philipp R, Engelmann D, Schulz-Kindermann F, Rosenberger C, Oechsle K, Härter M, Wegscheider K, Lordick F, Lo C, Hales S, Rodin G, Mehnert A (2015) Efficacy of a brief manualized intervention Managing Cancer and Living Meaningfully (CALM) adapted to German cancer care settings: study protocol for a randomized controlled trial. BMC Cancer 15:592. https://doi.org/10.1186/s12885-015-1589-y CrossRefPubMedPubMedCentralGoogle Scholar
- 19.Wade DT, Vergis E (1999) The Short Orientation-Memory-Concentration Test: a study of its reliability and validity. Clin Rehabil 13(2):164–170CrossRefGoogle Scholar
- 20.Lo C, Walsh A, Mikulincer M, Gagliese L, Zimmermann C, Rodin G (2009) Measuring attachment security in patients with advanced cancer: psychometric properties of a modified and brief Experiences in Close Relationships scale. Psycho-Oncology 18(5):490–499. https://doi.org/10.1002/pon.1417 CrossRefPubMedGoogle Scholar
- 21.Philipp R, Vehling S, Scheffold K, Grünke B, Härter M, Mehnert A, Oechsle K, Schulz-Kindermann F, Lo C (2017) Attachment insecurity in advanced cancer patients: psychometric properties of the German version of the brief Experiences in Close Relationships scale (ECR-M16-G). J Pain Symptom Manag 54(4):555–562. https://doi.org/10.1016/j.jpainsymman.2017.07.026 CrossRefGoogle Scholar
- 22.Löwe B, Kroenke K, Herzog W, Gräfe K (2004) Measuring depression outcome with a brief self-report instrument: sensitivity to change of the Patient Health Questionnaire (PHQ-9). J Affect Disord 81(1):61–66. https://doi.org/10.1016/S0165-0327(03)00198-8 CrossRefPubMedGoogle Scholar
- 23.Engelmann D, Scheffold K, Friedrich M, Hartung TJ, Schulz-Kindermann F, Lordick F, Schilling G, Lo C, Rodin G, Mehnert A (2016) Death-related anxiety in patients with advanced cancer: validation of the German version of the Death and Dying Distress Scale. J Pain Symptom Manag 52(4):582–587. https://doi.org/10.1016/j.jpainsymman.2016.07.002 CrossRefGoogle Scholar
- 24.Peterman AH, Fitchett G, Brady MJ, Hernandez L, Cella D (2002) Measuring spiritual well-being in people with cancer: the functional assessment of chronic illness therapy--Spiritual Well-being Scale (FACIT-Sp). Ann Behav Med 24(1):49–58CrossRefGoogle Scholar
- 25.Baron RM, Kenny DA (1986) The moderator-mediator variable distinction in social psychological research. J Pers Soc Psychol 51(6):1173–1182CrossRefGoogle Scholar
- 26.Hayes AF (2009) Beyond Baron and Kenny: statistical mediation analysis in the new millennium. Commun Monogr 76(4):408–420. https://doi.org/10.1080/03637750903310360 CrossRefGoogle Scholar
- 27.Hayes AF (2017) Introduction to mediation, moderation, and conditional process analysis: a regression-based approach, 2nd edn. The Guilford Publications, New YorkGoogle Scholar
- 28.Hayes AF, Preacher KJ (2014) Statistical mediation analysis with a multicategorical independent variable. Br J Math Stat Psychol 67(3):451–470. https://doi.org/10.1111/bmsp.12028 CrossRefPubMedGoogle Scholar
- 29.Granqvist P, Ivarsson T, Broberg AG, Hagekull B (2007) Examining relations among attachment, religiosity, and new age spirituality using the adult attachment interview. Dev Psychol 43(3):590–601. https://doi.org/10.1037/0012-1649.43.3.590 CrossRefPubMedGoogle Scholar
- 30.Granqvist P, Mikulincer M, Shaver PR (2010) Religion as attachment: normative processes and individual differences. Personal Soc Psychol Rev 14(1):49–59. https://doi.org/10.1177/1088868309348618 CrossRefGoogle Scholar
- 31.Mikulincer M (1998) Attachment working models and the sense of trust: an exploration of interaction goals and affect regulation. J Pers Soc Psychol 74(5):1209–1224. https://doi.org/10.1037/0022-3514.74.5.1209 CrossRefGoogle Scholar
- 32.Mikulincer M, Shaver PR, Pereg D (2003) Motiv Emot 27(2):77–102. https://doi.org/10.1023/A:1024515519160 CrossRefGoogle Scholar
- 33.Ciechanowski PS (2002) Attachment theory: a model for health care utilization and somatization. Psychosom Med 64(4):660–667. https://doi.org/10.1097/01.PSY.0000021948.90613.76 CrossRefPubMedGoogle Scholar
- 34.Kunsmann-Leutiger E, Loetz C, Frick E, Petersen Y, Müller JJ (2018) Attachment patterns affect spiritual coping in palliative care. J Hosp Palliat Nurs 20(4):385–391. https://doi.org/10.1097/NJH.0000000000000455 CrossRefPubMedGoogle Scholar
- 35.Meuti V, Aceti F, Giacchetti N, Carluccio GM, Zaccagni M, Marini I, Giancola O, Ciolli P, Biondi M (2015) Perinatal depression and patterns of attachment: a critical risk factor? Depress Res Treat 2015:105012. https://doi.org/10.1155/2015/105012 CrossRefPubMedPubMedCentralGoogle Scholar
- 36.Fraley RC, Shaver PR (2000) Adult romantic attachment: theoretical developments, emerging controversies, and unanswered questions. Rev Gen Psychol 4(2):132–154. https://doi.org/10.1037//1089-2680.4.2.132 CrossRefGoogle Scholar
- 37.Maunder RG, Hunter JJ (2009) Assessing patterns of adult attachment in medical patients. Gen Hosp Psychiatry 31(2):123–130. https://doi.org/10.1016/j.genhosppsych.2008.10.007 CrossRefPubMedGoogle Scholar
- 38.Ravitz P, Maunder R, Hunter J, Sthankiya B, Lancee W (2010) Adult attachment measures: a 25-year review. J Psychosom Res 69(4):419–432. https://doi.org/10.1016/j.jpsychores.2009.08.006 CrossRefPubMedGoogle Scholar
- 39.Büssing A, Ostermann T, Koenig HG (2007) Relevance of religion and spirituality in German patients with chronic diseases. Int J Psychiatry Med 37(1):39–57. https://doi.org/10.2190/60W7-1661-2623-6042 CrossRefPubMedGoogle Scholar
- 40.Büssing A, Janko A, Baumann K, Hvidt NC, Kopf A (2013) Spiritual needs among patients with chronic pain diseases and cancer living in a secular society. Pain Med 14(9):1362–1373. https://doi.org/10.1111/pme.12198 CrossRefPubMedGoogle Scholar
- 41.Mikulincer M, Shaver PR (2007) Boosting attachment security to promote mental health, prosocial values, and inter-group tolerance. Psychol Inq 18(3):139–156. https://doi.org/10.1080/10478400701512646 CrossRefGoogle Scholar
- 42.Maunder RG, Hunter JJ (2016) Can patients be ‘attached’ to healthcare providers? An observational study to measure attachment phenomena in patient–provider relationships. BMJ Open 6(5):e011068. https://doi.org/10.1136/bmjopen-2016-011068 CrossRefPubMedPubMedCentralGoogle Scholar
- 43.LeMay K, Wilson KG (2008) Treatment of existential distress in life threatening illness: a review of manualized interventions. Clin Psychol Rev 28(3):472–493. https://doi.org/10.1016/j.cpr.2007.07.013 CrossRefPubMedGoogle Scholar
- 44.Schulz-Kindermann F, Vehling S (2017) Sinnbasierte Interventionen bei fortgeschritten erkrankten Patienten. Onkologe 23(12):1011–1015. https://doi.org/10.1007/s00761-017-0281-z CrossRefGoogle Scholar
- 45.Hales S, Lo C, Rodin G (2010) Managing Cancer and Living Meaningfully (CALM): treatment manual: an individual psychotherapy for patients with advanced cancer. Psychosocial Oncology and Palliative Care. Princess Margaret Hospital, University Health Network, TorontoGoogle Scholar