Why 0.9% saline is not normal
Dr. Hayes in an excellent review article of “Ab-normal saline in abnormal kidney function: risks and alternatives” has mentioned that normal saline is hypertonic capable of causing hypernatremia and metabolic acidosis . Subsequently, Dr. Mortiz has discussed in the letter to the editor entitled as “Why 0.9% saline is isotonic” that normal saline is isotonic after the correction of osmolarity to osmolality . There are some inadequacy in the letter of Dr. Mortiz that needs to be described.
- 1.Moritz ML (2018) Why 0.9% saline is isotonic: understanding of the aqueous phase of plasma and the difference between osmolarity and osmolality. Pediatr Nephrol. https://doi.org/10.1007/s00467-018-4084-2
- 2.Hayes (2018) Ab-normal saline in abnormal kidney function: risks and alternatives. Pediatr Nephrol. https://doi.org/10.1007/s00467-018-4008-1