Pediatric Nephrology

, Volume 33, Issue 4, pp 705–712 | Cite as

Barriers for implementation of intensified hemodialysis: survey results from the International Pediatric Dialysis Network

  • Julia ThumfartEmail author
  • Dominik Müller
  • Steffen Wagner
  • Anuradha Jayanti
  • Dagmara Borzych-Duzalka
  • Franz Schaefer
  • Bradley Warady
  • Claus Peter Schmitt
Original Article



In patients on conventional hemodialysis (HD), morbidity is high and quality of life is poor. Intensified HD programs have been developed to help overcome these shortcomings, , but very few pediatric dialysis centers have reported the implementation of such a HD program.


An online survey was sent to all 221 pediatric dialysis centers which participate in the International Pediatric Dialysis Network (IPDN). The aim of the survey was to assess the attitude of pediatric nephrologists towards intensified HD, the penetrance of intensified HD into their clinical practice and barriers to implementation.


Of the 221 pediatric dialysis centers sent the survey, respondents from 61% (134) replied. Among these respondents, 69% acknowledged being aware of the evidence in support of the use of intensified HD, independent of whether intensified HD was offered at their own center, and 50% associated the use of daily nocturnal HD with the best overall patient outcome. In contrast, only 2% of respondents were in favor of conventional HD. Overall, 38% of the respondents stated that at their center intensified HD is prescribed to a subgroup of patients, most commonly in the form of short daily HD sessions. The most important barriers to expansion of intensified HD programs were lack of adequate funding (66%) and shortage of staff (63%), whereas lack of expertise and of motivation were reported infrequently as obstacles (21 and 14%, respectively).


Intensified HD is considered by many pediatric nephrologists to be the dialysis modality most likely associated with the best patient outcome. The limited use of this treatment approach highlights the importance of defining and successfully addressing the barriers to implementation.


Children Home dialysis Financial barriers Intensified hemodialysis Nocturnal hemodialysis 



We are grateful to Dr. Sandip Mitra for providing help with the survey.

Authors’ contributions

All listed authors contributed to this article.


This survey was financially supported by the German Society of Pediatric Nephrology GPN. IPDN is financially supported by Fresenius and Baxter Healthcare.

Compliance with ethical standards

Conflict of interest

CP Schmitt received travel grants and lecturing honoraria from Fresenius and Baxter and consulting honoraria from Baxter. All other authors have no conflicts of interest to declare.

Supplementary material

467_2017_3831_MOESM1_ESM.docx (24 kb)
Supplementary Table 1 (DOCX 23 kb)


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Copyright information

© IPNA 2017

Authors and Affiliations

  1. 1.Department of Pediatric NephrologyCharité-Universitätsmedizin BerlinBerlinGermany
  2. 2.INWT Statistics GmbHBerlinGermany
  3. 3.Manchester Institute of Nephrology & TransplantationManchester Royal InfirmaryManchesterUK
  4. 4.Department Pediatrics, Nephrology & HypertensionMedical University of GdanskGdanskPoland
  5. 5.Department of Pediatric NephrologyUniversity Hospital for Pediatric and Adolescent MedicineHeidelbergGermany
  6. 6.Division of Pediatric NephrologyChildren’s Mercy HospitalKansas CityUSA

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