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Pediatric Nephrology

, Volume 21, Issue 8, pp 1189–1193 | Cite as

Tuberous sclerosis complex and renal angiomyolipoma: case report and review of the literature

  • Elisabeth B. Winterkorn
  • Ghaleb H. Daouk
  • Sudha Anupindi
  • Elizabeth A. ThieleEmail author
Brief Report

Abstract

A 5-year-old boy with a known diagnosis of tuberous sclerosis complex was found to have an enlarging renal mass on routine ultrasound. He was diagnosed with an angiomyolipoma (AML) and scheduled for close observation. Follow-up magnetic resonance imaging demonstrated the AML to be significantly enlarged and hypervascular. Selective arterial embolization of the tumor was performed, which resulted in an appropriate decrease in tumor size. Angiomyolipoma is a known and well-described complication of the tuberous sclerosis complex that is usually found among patients in their adolescent and adult years. The case presented here illustrates the need for early and repeated renal imaging of younger pediatric patients with tuberous sclerosis. Our experience adds to the literature on young pediatric patients requiring embolization for treatment of large renal angiomyolipomas.

Keywords

Tuberous sclerosis complex Angiomyolipoma Selective arterial embolization 

Abbreviations

AML

angiomyolipoma

ESRD

end-stage renal disease

RCC

renal cell carcinoma

SAE

selective arterial embolization

TSC

tuberous sclerosis complex

Notes

Acknowledgements

This study was made possible by the support of the Carol and James Herscot Center for Tuberous Sclerosis Complex.

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Copyright information

© IPNA 2006

Authors and Affiliations

  • Elisabeth B. Winterkorn
    • 1
  • Ghaleb H. Daouk
    • 2
  • Sudha Anupindi
    • 3
  • Elizabeth A. Thiele
    • 1
    • 4
    Email author
  1. 1.Departments of Neurology and PediatricsMassachusetts General HospitalBostonUSA
  2. 2.Department of Pediatric NephrologyMassachusetts General HospitalBostonUSA
  3. 3.Department of Pediatric RadiologyMassachusetts General HospitalBostonUSA
  4. 4.The Herscot Center for Tuberous Sclerosis ComplexBostonUSA

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