Pediatric Nephrology

, Volume 21, Issue 6, pp 884–884 | Cite as

Reply to the letter from K. K. Lau and N. M. Delos Santos

  • Masashi NishidaEmail author
  • Hidekazu Kawakatsu
  • Yasuko Okumura
  • Kenji Hamaoka
Letter to the Editors


Public Health Proteinuria Large Study Favorable Outcome Clinical Entity 
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We are most grateful to Dr. Lau for his comment [1] on our Letter to the Editors regarding asymptomatic C1q nephropathy [2]. Among their patients, three African–American patients presented with incidental proteinuria. However, in contrast to our patients, all of these three patients ultimately had nephrotic range proteinuria. In addition, they all showed focal segmental glomerulosclerosis in histology, and had less favorable outcomes than our patients. Although the reason for this discrepancy is unclear, their data, as well as our observations, show that a considerable number of patients with asymptomatic proteinuria may have C1q nephropathy. As they mentioned in the Letter, larger studies of well-characterized patients and longer follow-up times for this clinical entity are necessary.


  1. 1.
    Lau KK, Delos Santos NM (2006) Pediatric C1q nephropathy and incidental proteinuria. Pediatr Nephrol CrossRefGoogle Scholar
  2. 2.
    Nishida M, Kawakatsu H, Okumura Y, Hamaoka K (2005) C1q nephropathy with asymptomatic urine abnormalities. Pediatr Nephrol 20:1669–1670CrossRefGoogle Scholar

Copyright information

© IPNA 2006

Authors and Affiliations

  • Masashi Nishida
    • 1
    Email author
  • Hidekazu Kawakatsu
    • 2
  • Yasuko Okumura
    • 1
  • Kenji Hamaoka
    • 1
  1. 1.Department of Pediatric Cardiology and NephrologyKyoto Prefectural University of Medicine Graduate School of Medical ScienceKamigyo-kuJapan
  2. 2.Department of PediatricsKyoto City HospitalKyotoJapan

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