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Surgical Endoscopy

, Volume 33, Issue 1, pp 52–57 | Cite as

Feasibility of hand-assisted laparoscopic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancy

  • George I. SaltiEmail author
  • Samer A. Naffouje
Article
  • 97 Downloads

Abstract

Background

In light of the modern surgical trend towards minimally invasive surgery, we aim to assess the feasibility of hand-assisted laparoscopic (HAL) cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in peritoneal surface malignancy (PSM).

Methods

Patients with PSM secondary to colorectal cancer or pseudomyxoma peritonei with peritoneal cancer index (PCI) of ≤ 10 were considered for HAL CRS and HIPEC. One patient had PCI of 15 but based on the disease distribution laparoscopic-assisted CRS and HIPEC was thought to be feasible, thus was also included. These patients were compared to matched controls who underwent open CRS and HIPEC for similar pathologies. Matching was performed on age and PCI to reflect a comparable complexity of the operation, and tumor grade for comparable risk of disease recurrence.

Results

Eleven patients were included in each group. In both groups, mean PCI was 4.1, mean age was 58.5 years, and 81.8% were well-moderately differentiated tumors. Complete cytoreduction was achieved in all patients. Upon comparison, HAL patients had significantly less blood loss and 3-day shorter hospitalization. No difference was demonstrated in operative time, number of visceral resections, and rate of omentectomy/peritonectomy. Also, no difference was detected in morbidities and 30-day readmission rates. No intraperitoneal recurrences have been reported in the HAL group after a median follow-up of 11 months.

Conclusion

HAL CRS and HIPEC is a feasible procedure and can be considered for PSM with low PCI. It offers very acceptable and comparable short-term outcomes to the conventional open approach.

Keywords

CRS and HIPEC Hand-assisted laparoscopy Peritoneal surface malignancy 

Notes

Compliance with ethical standards

Conflict of interest

Dr. George I. Salti and Dr. Samer A. Naffouje have no conflicts of interest or financial ties to disclose.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Surgical OncologyThe University of Illinois at Chicago Hospital and Health Sciences SystemChicagoUSA
  2. 2.Department of Surgical OncologyEdward Hospital Cancer CenterNapervilleUSA
  3. 3.Department of General SurgeryUniversity of Illinois Hospital and Health Sciences SystemChicagoUSA

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