Customized airway stenting for bronchopleural fistula after pulmonary resection by interventional technique: single-center study of 148 consecutive patients
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Bronchopleural fistula after pulmonary resection is a serious complication, with major impact on the quality of life and survival. This study aims to evaluate the efficacy and safety of customized airway stenting in the treatment of bronchopleural fistula.
A series of airway stents for dedicated bronchopleural fistula occlusion were designed after taking into account the anatomical and pathophysiological features of post-pulmonary resection fistulas and the shortcomings of airway stents currently available. The fistulas were occluded with the bullet head or a special part of the covered airway stent. Successful stenting was defined as immediate cessation of air leak from the residual cavity after stenting. The results were retrospectively analyzed.
Airway occlusion stenting was successful on the first attempt in 143/148 (96.6%) patients with bronchopleural fistulas. In the remaining 5 patients, occlusion was successful only on the second try. At follow-up 30 days after stenting, 141 patients reported relief in symptoms. No choking, laryngeal edema, or airway rupture occurred in any patient during stent insertion or removal; 2 patients developed hemorrhage during stent removal.
Airway occlusion stenting appears to be a feasible and effective technique for treatment of bronchopleural fistula.
KeywordsLung cancer Pulmonary resection Bronchopleural fistula Stent Interventional radiology
We thank the pulmonologists at our hospital for their assistance in this study.
Compliance with ethical standards
Xinwei Han, Meipan Yin, Lei Li, Ming Zhu, Kewei Ren, Yu Qi, Xiangnan Li, and Gang Wu have no conflicts of interest or financial ties to disclose.
This study was approved by the Ethics Committee and Medical Records Management Department of the First Affiliated Hospital of Zhengzhou University, Henan, China (Registration No. 2015-07).
All patients gave written informed consent.
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