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Is transnasal endoscope-assisted endoscopic submucosal dissection for gastric neoplasm useful in training beginners? A prospective randomized trial

Abstract

Background

The main problem in performing endoscopic submucosal dissection (ESD) of gastric neoplasms is that it is technically difficult, especially for beginners.

Methods

A total of 51 patients were randomly assigned to undergo transnasal endoscope-assisted or routine ESD performed by two endoscopists inexperienced in ESD while supervised by one expert.

Results

Total procedure time (p = 0.330), complete resection rate (p = 0.977), and complication rate (p = 0.157) were similar for the patients who underwent transnasal endoscope-assisted and routine ESD, but bleeding control time was significantly longer in the transnasal endoscope-assisted ESD group (p = 0.002). Three and six patients in the transnasal endoscope-assisted and routine ESD groups, respectively, were “dropped out” during the procedures (p = 0.291). The endoscopists tended to regard the traction with the transnasal endoscope as more useful for large tumors (p = 0.062). Bleeding control in patients who underwent the transnasal endoscope-assisted ESD was significantly longer for patients with tumors located in the anterior wall, posterior wall, and lesser curvature of the stomach (p = 0.001).

Conclusion

Transnasal endoscope-assisted ESD does not result in improved outcomes when performed by beginners, except for some large tumors. The traction method used by beginners was not superior to proper supervision and advice by an expert during ESD and allowing the expert to perform the procedure when the risk of complications is high or the procedure is delayed.

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Disclosures

J. Y. Ahn, K. D. Choi, J. H. Lee, J. Y. Choi, M-.Y. Kim, K-.S. Choi, D. H. Kim, H. J. Song, G. H. Lee, H-.Y. Jung, J-.H. Kim, S. Baek have no conflicts of interest or financial ties to disclose.

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Correspondence to Ji Yong Ahn.

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Ahn, J.Y., Choi, K.D., Lee, J.H. et al. Is transnasal endoscope-assisted endoscopic submucosal dissection for gastric neoplasm useful in training beginners? A prospective randomized trial. Surg Endosc 27, 1158–1165 (2013). https://doi.org/10.1007/s00464-012-2567-y

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Keywords

  • Endoscopy
  • Dissection
  • Stomach neoplasms
  • Adenoma