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Use of fibrin glue (Tissucol) as a hemostatic in laparoscopic conservative treatment of spleen trauma

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This study aimed to evaluate the effect of fibrin glue in laparoscopic spleen-preserving procedures for traumatic rupture.


From January 2002 to December 2005, six laparoscopic spleen-preserving procedures were performed for traumatic rupture using fibrin glue. Two of the cases had previous middle and lower abdominal surgery. Survey of the abdominal cavity was performed by inserting two 5- to 12-mm trocars, one 5-mm trocar, and a 30° scope. A complete survey of all the patients was performed.


None of the patients required laparotomy, and no postoperative bleeding occurred. The fibrin sealant achieved immediate hemostasis, and all the patients recovered without further splenic bleeding. The mean postoperative stay was 4.3 days (range, 4–5 days). All the patients were followed up for 3 to 12 months. Postoperative immunoglobulin scanning, ultrasonography, and computed tomography (CT) results were normal.


Laparoscopic management of spleen trauma can be used once a positive diagnosis has been made. It is useful for assessing the degree of splenic injury. A laparoscopic spleen-preserving procedure can be used safely for patients with stable vital data. It is an effective procedure for the evaluation and treatment of hemodynamically stable patients with splenic injuries for whom nonoperative treatment is controversial. The topical application of a fibrin sealant in splenic trauma achieves definitive hemostasis safely, rapidly, and reliably. It also is simple to use in either laparoscopic or open procedures.

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Correspondence to S. Olmi.

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An erratum to this article can be found at http://dx.doi.org/10.1007/s00464-007-9468-5

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Olmi, S., Scaini, A., Erba, L. et al. Use of fibrin glue (Tissucol) as a hemostatic in laparoscopic conservative treatment of spleen trauma. Surg Endosc 21, 2051–2054 (2007). https://doi.org/10.1007/s00464-007-9288-7

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  • Diagnostic laparoscopy
  • Fibrin glue
  • Laparoscopy
  • Spleen preserve
  • Spleen rupture
  • Trauma