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The implication of topology for protein structure and aggregation

Abstract

For proteins, it is discussed which intrinsic dynamical modes can be present when all static forces are screened. Excitations involving a wringing of the polypeptide chain around its path exists. It is suggested that the existence of such wringons is the underlying cause for the uniqueness of protein folding, and that they may be determinant for aggregation.

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Correspondence to Jakob Bohr.

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Bohr, J., Bohr, H.G. The implication of topology for protein structure and aggregation. Z Phys D - Atoms, Molecules and Clusters 40, 186–189 (1997). https://doi.org/10.1007/s004600050190

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PACS

  • 02.40A
  • 87.15.By
  • 87.15.Da