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Early Radiation Effects on Tongue Function for Patients with Nasopharyngeal Carcinoma: A Preliminary Study


The purpose of this study was to investigate early radiation effects on tongue function for patients with nasopharyngeal carcinoma (NPC) and to provide a scientific database for early intervention plans. Twelve subjects with NPC and 12 age- and sex-matched normal subjects were included. Tongue maximum isometric strength and endurance at 50% of maximum strength were obtained once from normal subjects with the Iowa Oral Performance Instrument (IOPI) and twice from the NPC subjects: before and 2 months after radiation treatment. No significant differences were found in tongue function evaluation for normal or NPC groups in either pre- or post-treatments. However, this study showed that significant decreases in tongue function may not start until 2 months after treatment.

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This study was supported by a grant from the National Science Council (NSC) (92-2218-E-227-001).

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Correspondence to Sheng Hwa Chen.

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Chang, C., Chen, S.H., Ko, J. et al. Early Radiation Effects on Tongue Function for Patients with Nasopharyngeal Carcinoma: A Preliminary Study. Dysphagia 23, 193–198 (2008).

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  • Radiation
  • Nasopharyngeal carcinoma
  • Tongue function
  • Tongue strength
  • Tongue endurance
  • Deglutition
  • Deglutition disorders