A minor proportion of patients with achalasia eventually have a neoplasm and, as a consequence, pseudoachalasia is diagnosed. A neoplasm may either involve gastrointestinal junction or present a paraneoplastic effect. Over the global diagnoses of achalasia issued in 5 years of experience in our motility unit, we have found 13% (3/23 cases) of pseudoachalasia (2–4% in previous series, probably due to the fact that the population assisted was mainly composed of elderly patients). The origin of the neoplasm was bladder, prostate and metastases from epidermoid carcinoma of vocal chord. Treatment of primary neoplasm, besides classical approach (with dilatation of botulinum injection) may help in the resolution of this clinical disorder.
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Ulla, J.L., Fernandez-Salgado, E., Alvarez, V. et al. Pseudoachalasia of the Cardia Secondary to Nongastrointestinal Neoplasia. Dysphagia 23, 122–126 (2008). https://doi.org/10.1007/s00455-007-9104-5
- Urologic neoplasm
- Paraneoplasic syndrome
- Deglutition disorders