Recent data show that during development protein zero, P0, the most abundant peripheral nerve myelin protein, is detecable long before myelination. In particular, the expression of P0 in a fraction of migrating neural crest reveals progenitor cell heterogeneity in the developing PNS. Here we review the regulation and potential function of P0 during peripheral gliogenesis.
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Received: 2 October 1997 / Accepted: 28 November 1997
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Sommer, L., Suter, U. The glycoprotein P0 in peripheral gliogenesis. Cell Tissue Res 292, 11–16 (1998). https://doi.org/10.1007/s004410051029
- Key words Protein zero
- Peripheral gliogenesis
- Neural crest