Prospects and modalities for the treatment of genetic ocular anomalies

  • Cheryl Y. Gregory-EvansEmail author
  • Xia Wang
  • Kevin Gregory-Evans
Original Investigation
Part of the following topical collections:
  1. Eye Genetics
  2. Eye Genetics
  3. Eye Genetics


Over the last three decades, genetic studies have made great strides toward the identification of genes and genetic mechanisms underlying congenital disorders of the eye. However, despite the vast knowledge available this has not translated into treatments to prevent or repair the damage in the clinical setting. Recently, new research in technologies, such as tissue regeneration, next generation designer drugs, and genome editing, have become available for some genetic disorders that might be applicable to congenital ocular diseases in the near future. Here, we provide an overview of the emerging therapeutic modalities and the future prospects they hold for debilitating ocular defects.


Compliance with ethical standards

Conflict of interest

The authors declare there is no conflict of interest.


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© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Ophthalmology and Visual SciencesUniversity of British ColumbiaVancouverCanada

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