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At what rate do new premutation alleles arise at the fragile X locus?

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We are grateful to Amy Cronister for sharing additional data on the size distribution of the intermediate alleles initially reported in Cronister et al. (2008). This research was supported by National Institutes of Health (NIH) grants HD002274 and GM077464. DPG was supported in part by the Jaconnette L. Tietze Young Scientist Award.

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Correspondence to Diane P. Genereux.

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Genereux, D.P., Laird, C.D. At what rate do new premutation alleles arise at the fragile X locus?. Hum Genet 132, 715–717 (2013).

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  • Mutation Rate
  • High Mutation Rate
  • Intermediate Allele
  • Premutation Allele
  • Mutation Rate Estimate