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Acanthamoeba keratitis in Porto Alegre (southern Brazil): 28 cases and risk factors


The increasing use of contact lenses worldwide has led to an increase in cases of Acanthamoeba keratitis, which are often associated with inappropriate cleaning of contact lenses and lens cases. This study aimed to retrospectively review 28 cases of Acanthamoeba keratitis in Porto Alegre (southern Brazil) and identify the risk factors and clinical outcomes of affected patients. Most patients had higher education (66.6%), all were users of contact lenses, mostly women (67.9%). Most patients were soft contact lens wearers (66.7%) and 85.7% used multipurpose cleaning solutions. Sixteen patients (64.0%) used to wear contact lenses while swimming and/or bathing. Pain was the most common symptom (92.6%). For treatment, patients used polyhexamethylene biguanide drops (92.6%), propamidine isethionate drops (81.5%), chlorhexidine drops (55.6%), topical corticosteroids (63.0%), and systemic corticosteroids (37.0%). Herpes simplex keratitis was the most common misdiagnosis (72.7%). The majority of patients (76.0%) underwent a corneal transplant to control the disease.

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The authors are grateful to the staff of the Department of Microbiology, Immunology and Parasitology of the Universidade Federal do Rio Grande do Sul and the Ophthalmology Department of the Hospital de Clínicas de Porto Alegre (HCPA) for their assistance.


The authors are grateful to the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and Fundo de Incentivo à Pesquisa e Eventos (FIPE/HCPA) for the financial support

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Correspondence to Marilise Brittes Rott.

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dos Santos, D.L., Kwitko, S., Marinho, D.R. et al. Acanthamoeba keratitis in Porto Alegre (southern Brazil): 28 cases and risk factors. Parasitol Res 117, 747–750 (2018). https://doi.org/10.1007/s00436-017-5745-y

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  • Acanthamoeba
  • Contact lenses
  • Corneal transplantation
  • Keratitis