What’s new in nerve sheath tumors

  • Anders Meyer
  • Steven D. BillingsEmail author
Review Article


Peripheral nerve sheath tumors are commonly encountered and frequently pose challenges to the pathologist and the clinician. This review discusses the wide range of entities with an emphasis on new discoveries in the past decade. Clinical, histologic, immunohistochemical, and pathogenetic findings are discussed with an emphasis on clinical implications and differential diagnosis.


Nerve sheath tumor Neurofibroma Perineurioma Granular cell tumor Schwannoma Malignant melanotic nerve sheath tumor Malignant peripheral nerve sheath tumor 


Author contributions

AM and SB contributed substantially to the conception and design of the work. AM and SB contributed substantially to the research, drafting, and revision of the work. AM and SB both approve of the submitted version and agree to give final approval to the final version to be published. AM and SB agree to be accountable for all aspects of the work. All authors contributed according to ICMJE standards.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.University of KansasKansas cityUSA
  2. 2.Cleveland ClinicClevelandUSA

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