Letter to the editor: reply to Antonio Ieni “Intratumoral HER2 heterogeneity in early gastric carcinomas: potential bias in therapeutical management”
Letter to the Editor
First Online:
- 31 Downloads
Notes
Authors contributions
Kazuki Kanayama: writing—original draft, writing–review and editing.
Hiroshi Imai: writing—review and editing.
Eri Usugi: writing—review and editing.
Taizo Shiraishi: writing—review and editing.
Yoshifumi S. Hirokawa: writing—original draft, writing—review and editing.
Masatoshi Watanabe: writing—review and editing.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflicts of interest.
References
- 1.Ieni A, Barresi V, Caltabiano R, Caleo A, Bonetti LR, Lanzafame S, Zeppa P, Caruso RA, Tuccari G (2014) Discordance rate of HER2 status in primary gastric carcinomas and synchronous lymph node metastases: a multicenter retrospective analysis. Int J Mol Sci 15:22331–22341. https://doi.org/10.3390/ijms151222331 CrossRefGoogle Scholar
- 2.Ieni A, Barresi V, Rigoli L, Caruso RA, Tuccari G (2015) HER2 status in premalignant, early, and advanced neoplastic lesions of the stomach. Dis Markers 2015:234851. https://doi.org/10.1155/2015/234851 CrossRefGoogle Scholar
- 3.Kanayama K, Imai H, Usugi E, Shiraishi T, Hirokawa YS, Watanabe M (2018) Association of HER2 gene amplification and tumor progression in early gastric cancer. Virchows Arch 473:559–565. https://doi.org/10.1007/s00428-018-2433-y CrossRefGoogle Scholar
- 4.Kanayama K, Imai H, Yoneda M, Hirokawa YS, Shiraishi T (2016) Significant intratumoral heterogeneity of human epidermal growth factor receptor 2 status in gastric cancer: a comparative study of immunohistochemistry, FISH, and dual-color in situ hybridization. Cancer Sci 107:536–542. https://doi.org/10.1111/cas.12886 CrossRefGoogle Scholar
- 5.Yan Y, Lu L, Liu C, Li W, Liu T, Fu W (2015) HER2/neu over-expression predicts poor outcome in early gastric cancer without lymph node metastasis. Clin Res Hepatol Gastroenterol 39:121–126. https://doi.org/10.1016/j.clinre.2014.06.019 CrossRefGoogle Scholar
- 6.Cao L, Hu X, Zhang Y, Huang G (2011) Adverse prognosis of clustered-cell versus single-cell micrometastases in pN0 early gastric cancer. J Surg Oncol 103:53–56CrossRefGoogle Scholar
- 7.Tanabe S, Hirabayashi S, Oda I, Ono H, Nashimoto A, Isobe Y, Miyashiro I, Tsujitani S, Seto Y, Fukagawa T, Nunobe S, Furukawa H, Kodera Y, Kaminishi M, Katai H (2017) Gastric cancer treated by endoscopic submucosal dissection or endoscopic mucosal resection in Japan from 2004 through 2006: JGCA nationwide registry conducted in 2013. Gastric Cancer 20:834–842. https://doi.org/10.1007/s10120-017-0699-4 CrossRefGoogle Scholar
- 8.Suzuki H, Oda I, Abe S, Sekiguchi M, Mori G, Nonaka S, Yoshinaga S, Saito Y (2016) High rate of 5-year survival among patients with early gastric cancer undergoing curative endoscopic submucosal dissection. Gastric Cancer 19:198–205. https://doi.org/10.1007/s10120-015-0469-0 CrossRefGoogle Scholar
- 9.Zeng Y-J, Zhang C-D, Dai D-Q (2015) Impact of lymph node micrometastasis on gastric carcinoma prognosis: a meta-analysis. World J Gastroenterol 21:1628–1635. https://doi.org/10.3748/wjg.v21.i5.1628 CrossRefGoogle Scholar
- 10.Japanese Gastric Cancer Association (2017) Japanese gastric cancer treatment guidelines 2014 (ver. 4). Gastric Cancer 20:1–19. https://doi.org/10.1007/s10120-016-0622-4 CrossRefGoogle Scholar
Copyright information
© Springer-Verlag GmbH Germany, part of Springer Nature 2019