Small-cell variant of renal oncocytoma with dominating solid growth pattern: a potential diagnostic pitfall
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Renal oncocytoma is a distinct benign renal tumour accounting approximately for 4% of all renal tumours. This neoplasm is easily recognizable in its classic form—polygonal cells with abundant granular eosinophilic cytoplasm, arranged in tubuloalveolar cystic pattern—whereas diagnostic difficulties may arise when it exhibits small cells with scant cytoplasm and hyperchromatic nuclei (so-called “oncoblasts”) . Although these small cells are rarely detectable in an otherwise classic renal oncocytoma [1, 3], there is the possibility that they may represent the dominating cell component . One of us (MM), by reviewing a large series of renal oncocytomas, found only 3 out of 134 tumours with a prominent (80% of the entire tumours in two cases and 50% in the other case) small-cell component, and the term “small-cell variant of renal oncocytoma” was proposed for these cases . We report a rare case of renal oncocytoma with a predominant small-cell component, accounting for...
KeywordsOncocytoma Small cell variant Kidney