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Planta

, 251:9 | Cite as

Phytochemistry and pharmacological activities of the genus Rhynchosia: a comprehensive review

  • Aluru RammohanEmail author
  • Guda Mallikarjuna Reddy
  • Baki Vijaya Bhaskar
  • Duvvuru Gunasekar
  • Grigory V. Zyryanov
Review
  • 32 Downloads

Abstract

Main conclusion

The genus Rhynchosia is a rich source of natural compounds especially flavonoids and prenylated isoflavonoids. Further experimental studies on Rhynchosia members may be result new and novel secondary metabolites with potent biological activities.

Abstract

Traditionally, medicinal plants have played a significant role on human life since ancient days. At present, natural compounds are the major source for the modern drug discovery owing to their therapeutic selectivity, minutest of side effects, inexpensive source and serve as lead molecules for the discovery of new drugs. Rhynchosia species (Fabaceae) are extensively circulated throughout the tropical and subtropical areas around the world. A few plants of this genus were used in traditional medicine for the treatment of various ailments such as antibacterial, antidiabetic, abortifacients, healing of wounds, hepatoprotective, remedial of boils, rheumatic pains and skin infections. The present review compiles traditional uses, isolated chemical compounds and pharmacological activities of Rhynchosia species. So far, in total, seventy-seven compounds were isolated from the genus Rhynchosia, including flavonoids, isoflavonoids, flavan-3-ols, xanthones, biphenyls, simple polyphenols and sterols. It is interesting to note that the genus Rhynchosia is a rich source of C-glycosylflavonoids and prenylated isoflavonoids. Further, phytochemical and pharmacological studies on this genus are required since only few species have been investigated so far.

Keywords

Flavonoids Phytochemistry Pharmacology Rhynchosia Traditional medicine 

Notes

Author contribution statement

The authors AR and DG were outline and collected the literature associated to the review. AR, GMR and BVB were performed manuscript writing and analysis the data. GVZ and DG contributed with their attentive discussions during manuscript preparation.

Compliance with ethical standards

Conflict of interest

All the authors declare no conflict of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Aluru Rammohan
    • 1
    • 2
    Email author
  • Guda Mallikarjuna Reddy
    • 1
  • Baki Vijaya Bhaskar
    • 3
  • Duvvuru Gunasekar
    • 2
  • Grigory V. Zyryanov
    • 1
    • 4
  1. 1.Department of Organic and Biomolecular ChemistryUral Federal University, Chemical Engineering InstituteYekaterinburgRussian Federation
  2. 2.Natural Products Division, Department of ChemistrySri Venkateswara UniversityTirupatiIndia
  3. 3.Department of Pathophysiology, The Key Immunopathology Laboratory of Guangdong ProvinceShantou University Medical CollegeShantouChina
  4. 4.Ural Division of the Russian Academy of SciencesI. Ya, Postovskiy Institute of Organic SynthesisYekaterinburgRussian Federation

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