Inverse association between changes in energetic cost of walking and vertical accelerations in non-metastatic breast cancer survivors
- 21 Downloads
With accelerometry, the utility to detect changes in physical activity are predicated on the assumption that walking energetics and gait mechanics do not change. The present work examined associations between changes (∆) in walking energetics, exercise self-efficacy, and several accelerometer-derived metrics.
Secondary analyses were performed among a sub-sample (n = 29) of breast cancer survivors participating in a larger randomized trial. During 4 min of treadmill walking (0.89 m s−1, 0% grade), indirect calorimetry quantified steady-state energy expenditure (EE), wherein, participants were fitted with a heart rate monitor and hip-worn triaxial accelerometer. Exercise self-efficacy was measured using a 9-item questionnaire, while vector magnitude (VM) and individual planes (e.g., mediolateral, vertical, and anteroposterior) of the movement were extracted for data analyses. Evaluations were made at baseline and after 3 months.
From baseline to 3 months, the energetic cost of walking (kcals min−1) significantly decreased by an average of − 5.1% (p = 0.001; d = 0.46). Conversely, VM significantly increased (p = 0.007; d = 0.53), exclusively due to greater vertical accelerations (acc) (+ 5.7 ± 7.8 acc; p = 0.001; d = 0.69). Changes in vertical accelerations were inversely and positively associated with ∆walking EE (r = − 0.37; p = 0.047) and ∆exercise self-efficacy (r = 0.39; p = 0.034), respectively.
Hip-worn accelerometers do not appear well-suited to correctly detect changes in ease of walking as evidenced by reduced energetic cost. Further research should determine if a divergence between measured EE and vertical accelerations could contribute to erroneous inferences in free-living physical activity.
KeywordsCardiovascular Energy expenditure Exercise training Non-metastatic Physical activity
We would like to recognize David R. Bryan, MA, and Sara Mansfield, MS, for their commitment and respective contributions. The authors also wish to express their appreciation to the participants for their willingness to complete this investigation.
SJC, LQR, HRB, LAN, and GRH participated in the execution of the study including, data analyses, drafting, review, and final approval of the manuscript.
This project was supported by the following funding sources: U01CA136859, R25CA047888, and P30DK056336.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- American College of Sports Medicine (2010) ACSM's Guidelines for Exercise Testing and Prescription. Lippincott, Williams, and Wilkins, BaltimoreGoogle Scholar
- Carter SJ, Hunter GR, Norian LA, Turan B, Rogers LQ (2018) Ease of walking associates with greater free-living physical activity and reduced depressive symptomology in breast cancer survivors: pilot randomized trial. Support Care Cancer 26:1675–1683. https://doi.org/10.1007/s00520-017-4015-y Google Scholar
- Elme A, Utriainen M, Kellokumpu-Lehtinen P et al (2013) Obesity and physical inactivity are related to impaired physical health of breast cancer survivors. Anticancer Res 33:1595–1602Google Scholar
- Gross AL, May BJ, Axilbund JE, Armstrong DK, Roden RB, Visvanathan K (2015) Weight change in breast cancer survivors compared to cancer-free women: a prospective study in women at familial risk of breast cancer. Cancer Epidemiol Biomarkers Prev 24:1262–1269. https://doi.org/10.1158/1055-9965.EPI-15-0212 CrossRefGoogle Scholar