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European Journal of Applied Physiology

, Volume 119, Issue 9, pp 2095–2103 | Cite as

Effect of different doses of supervised aerobic exercise on heart rate recovery in inactive adults who are overweight or obese: results from E-MECHANIC

  • Christoph Höchsmann
  • James L. Dorling
  • John W. Apolzan
  • Neil M. Johannsen
  • Daniel S. Hsia
  • Timothy S. Church
  • Corby K. MartinEmail author
Original Article

Abstract

Purpose

Heart rate recovery (HRR) after exercise is an independent risk factor for cardiovascular disease and mortality. Regular aerobic exercise can improve HRR, yet little is known regarding the dose necessary to promote increases. The aim was to assess the impact of different doses of vigorous-intensity aerobic exercise on HRR in individuals with overweight/obesity.

Methods

Data from 137 sedentary adults with overweight/obesity from E-MECHANIC were analyzed. Participants were randomized to either a moderate-dose exercise group (8 kcal/kg body weight/week; KKW), a high-dose exercise group (20 KKW), or a non-exercise control group. HRR was defined as the difference between peak heart rate (HR) during a graded exercise test and the HR after exactly 1 min of active recovery at 1.5 mph and level grade.

Results

Change in HRR did not differ significantly by exercise group; therefore, the data from both exercise groups were combined. The combined exercise group showed an improvement in HRR of 2.7 bpm (95% CI 0.1, 5.4; p = 0.04) compared to the control group. Those participants who lost more weight during the intervention (non-compensators) increased HRR by 6.2 bpm (95% CI 2.8, 9.5; p < 0.01) compared to those who lost less weight (compensators). Multiple linear regression models indicated that improvements in HRR are independently associated with increases in VO2peak (β = 0.4; 95% CI 0.1, 0.7; p = 0.04) but also influenced by concomitant weight loss (β = 0.6; 95% CI 0.2, 1.1; p = 0.01).

Conclusion

Exercise-induced improvements in 1-min HRR are likely due to increases in cardiorespiratory fitness as well as concomitant weight loss.

Keywords

Heart rate recovery Exercise Aerobic capacity Weight loss Autonomic function 

Abbreviations

ANCOVA

Analysis of covariance

BMI

Body mass index

bpm

Beats per minute

CI

Confidence interval

E-MECHANIC

The Examination of Mechanisms of Exercise-Induced Weight Compensation

HR

Heart rate

HRR

Heart rate recovery

KKW

Kilocalories per kilogram of body weight per week

METS

Metabolic equivalents

mph

Miles per hour

RPE

Ratings of perceived exertion

SD

Standard deviation

VO2peak

Peak oxygen uptake

Notes

Acknowledgements

The authors would like to thank participants for their time and commitment to the study.

Author contributions

CKM and TSC conceptualized and designed the study. DSH, NMJ, and JWA were responsible for data collection. CH performed statistical analyses and wrote the manuscript. CH, JD, and CKM interpreted the data and prepared the results for publication. All authors reviewed and edited the manuscript and approved the final version for publication.

Funding

Research reported in this publication was supported by the National Institutes of Health via the National Heart, Lung, and Blood Institute with the Multiple Principal Investigators being C. Martin and T. Church (R01 HL102166); NORC Center Grant P30 DK072476, entitled “Nutritional Programming: Environmental and Molecular Interactions” sponsored by NIDDK; and the National Institute of General Medical Sciences, which funds the Louisiana Clinical and Translational Science Center (U54 GM104940). C. Höchsmann is funded by an NIH NIDDK National Research Service Award (T32 DK064584).

Compliance with ethical standards

Conflict of interest

The authors report no conflicts of interests related to this study.

References

  1. Álvarez C, Ramírez-Campillo R, Martínez C et al (2017) Changes in the heart rate recovery to endurance effort after high intensity interval, strength, and concurrent exercise training in patients with insulin resistance. J Sports Med Phys Fit 57:1533–1540.  https://doi.org/10.23736/S0022-4707.16.06614-7 Google Scholar
  2. American College of Sports Medicine (2014) ACSM’s guidelines for exercise testing and prescription, 9th edn. Wolters Kluwer/Lippincott Williams & Wilkins Health, PhiladelphiaGoogle Scholar
  3. Barbosa Lins TC, Valente LM, Sobral Filho DC, Barbosa e Silva O (2015) Relation between heart rate recovery after exercise testing and body mass index. Rev Port Cardiol Orgao Soc Port Cardiol 34:27–33.  https://doi.org/10.1016/j.repc.2014.07.006 CrossRefGoogle Scholar
  4. Bellenger CR, Fuller JT, Thomson RL et al (2016) Monitoring athletic training status through autonomic heart rate regulation: a systematic review and meta-analysis. Sports Med Auckl N Z 46:1461–1486.  https://doi.org/10.1007/s40279-016-0484-2 CrossRefGoogle Scholar
  5. Borg GA (1982) Psychophysical bases of perceived exertion. Med Sci Sports Exerc 14:377–381Google Scholar
  6. Borresen J, Lambert MI (2008) Autonomic control of heart rate during and after exercise. Sports Med 38:633–646.  https://doi.org/10.2165/00007256-200838080-00002 CrossRefGoogle Scholar
  7. Brinkworth GD, Noakes M, Buckley JD, Clifton PM (2006) Weight loss improves heart rate recovery in overweight and obese men with features of the metabolic syndrome. Am Heart J 152:693.e1–6.  https://doi.org/10.1016/j.ahj.2006.07.019 CrossRefGoogle Scholar
  8. Carnethon MR, Sternfeld B, Liu K et al (2012) Correlates of heart rate recovery over 20 years in a healthy population sample. Med Sci Sports Exerc 44:273–279.  https://doi.org/10.1249/MSS.0b013e31822cb190 CrossRefGoogle Scholar
  9. Church TS, Earnest CP, Skinner JS, Blair SN (2007) Effects of different doses of physical activity on cardiorespiratory fitness among sedentary, overweight or obese postmenopausal women with elevated blood pressure: a randomized controlled trial. JAMA 297:2081–2091.  https://doi.org/10.1001/jama.297.19.2081 CrossRefGoogle Scholar
  10. Cole CR, Blackstone EH, Pashkow FJ et al (1999) Heart-rate recovery immediately after exercise as a predictor of mortality. N Engl J Med 341:1351–1357.  https://doi.org/10.1056/NEJM199910283411804 CrossRefGoogle Scholar
  11. Coote JH, White MJ (2015) CrossTalk proposal: Bradycardia in the trained athlete is attributable to high vagal tone. J Physiol 593:1745–1747.  https://doi.org/10.1113/jphysiol.2014.284364 CrossRefGoogle Scholar
  12. Curfman GD, Hillis LD (2003) A new look at cardiac exercise testing. N Engl J Med 348:775–776.  https://doi.org/10.1056/NEJMp030004 CrossRefGoogle Scholar
  13. Dimkpa U, Oji JO (2010) Association of heart rate recovery after exercise with indices of obesity in healthy, non-obese adults. Eur J Appl Physiol 108:695–699.  https://doi.org/10.1007/s00421-009-1276-2 CrossRefGoogle Scholar
  14. Garber CE, Blissmer B, Deschenes MR et al (2011) American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 43:1334–1359.  https://doi.org/10.1249/MSS.0b013e318213fefb CrossRefGoogle Scholar
  15. Giallauria F, Maresca L, Vitelli A et al (2015) Exercise training improves heart rate recovery in women with breast cancer. SpringerPlus 4:388.  https://doi.org/10.1186/s40064-015-1179-0 CrossRefGoogle Scholar
  16. Gimeno-Santos E, Rodriguez DA, Barberan-Garcia A et al (2014) Endurance exercise training improves heart rate recovery in patients with COPD. COPD 11:190–196.  https://doi.org/10.3109/15412555.2013.831401 CrossRefGoogle Scholar
  17. Johnson NP, Goldberger JJ (2012) Prognostic value of late heart rate recovery after treadmill exercise. Am J Cardiol 110:45–49.  https://doi.org/10.1016/j.amjcard.2012.02.046 CrossRefGoogle Scholar
  18. Jolly MA, Brennan DM, Cho L (2011) Impact of exercise on heart rate recovery. Circulation 124:1520–1526.  https://doi.org/10.1161/CIRCULATIONAHA.110.005009 CrossRefGoogle Scholar
  19. Kim M-K, Tanaka K, Kim M-J et al (2009) Exercise training-induced changes in heart rate recovery in obese men with metabolic syndrome. Metab Syndr Relat Disord 7:469–476.  https://doi.org/10.1089/met.2008.0086 CrossRefGoogle Scholar
  20. Knaier R, Niemeyer M, Wagner J et al (2019) Which cut-offs for secondary VO2max criteria are robust to diurnal variations? Med Sci Sports Exerc 51:1006–1013.  https://doi.org/10.1249/MSS.0000000000001869 CrossRefGoogle Scholar
  21. MacMillan JS, Davis LL, Durham CF, Matteson ES (2006) Exercise and heart rate recovery. Heart Lung 35:383–390.  https://doi.org/10.1016/j.hrtlng.2006.07.003 CrossRefGoogle Scholar
  22. Martin CK, Johnson WD, Myers CA et al (2019) Effect of different doses of supervised exercise on food intake, metabolism, and non-exercise physical activity: the E-MECHANIC randomized controlled trial. Am J Clin Nutr.  https://doi.org/10.1093/ajcn/nqz054 Google Scholar
  23. Matsuo T, Saotome K, Seino S et al (2014) Low-volume, high-intensity, aerobic interval exercise for sedentary adults: VO2max, cardiac mass, and heart rate recovery. Eur J Appl Physiol 114:1963–1972.  https://doi.org/10.1007/s00421-014-2917-7 CrossRefGoogle Scholar
  24. McAuley PA, Blaha MJ, Keteyian SJ et al (2016) Fitness, fatness, and mortality: the FIT (Henry Ford Exercise Testing) Project. Am J Med 129:960–965.e1.  https://doi.org/10.1016/j.amjmed.2016.04.007 CrossRefGoogle Scholar
  25. Medeiros WM, de Luca FA, de Figueredo Júnior AR et al (2018) Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, β-blocker therapy or both. Clin Physiol Funct Imaging 38:351–359.  https://doi.org/10.1111/cpf.12420 CrossRefGoogle Scholar
  26. Moholdt TT, Amundsen BH, Rustad LA et al (2009) Aerobic interval training versus continuous moderate exercise after coronary artery bypass surgery: a randomized study of cardiovascular effects and quality of life. Am Heart J 158:1031–1037.  https://doi.org/10.1016/j.ahj.2009.10.003 CrossRefGoogle Scholar
  27. Myers CA, Johnson WD, Earnest CP et al (2014) Examination of mechanisms (E-MECHANIC) of exercise-induced weight compensation: study protocol for a randomized controlled trial. Trials 15:212.  https://doi.org/10.1186/1745-6215-15-212 CrossRefGoogle Scholar
  28. Niederer D, Vogt L, Gonzalez-Rivera J et al (2015) Heart rate recovery and aerobic endurance capacity in cancer survivors: interdependence and exercise-induced improvements. Support Care Cancer 23:3513–3520.  https://doi.org/10.1007/s00520-015-2719-4 CrossRefGoogle Scholar
  29. Nishime EO, Cole CR, Blackstone EH et al (2000) Heart rate recovery and treadmill exercise score as predictors of mortality in patients referred for exercise ECG. JAMA 284:1392–1398.  https://doi.org/10.1001/jama.284.11.1392 CrossRefGoogle Scholar
  30. Qiu S, Cai X, Sun Z et al (2017) Heart rate recovery and risk of cardiovascular events and all-cause mortality: a meta-analysis of prospective cohort studies. J Am Heart Assoc.  https://doi.org/10.1161/JAHA.117.005505 Google Scholar
  31. Savonen KP, Kiviniemi V, Laaksonen DE et al (2011) Two-minute heart rate recovery after cycle ergometer exercise and all-cause mortality in middle-aged men. J Intern Med 270:589–596.  https://doi.org/10.1111/j.1365-2796.2011.02434.x CrossRefGoogle Scholar
  32. Stöggl TL, Björklund G (2017) High intensity interval training leads to greater improvements in acute heart rate recovery and anaerobic power as high volume low intensity training. Front Physiol 8:562.  https://doi.org/10.3389/fphys.2017.00562 CrossRefGoogle Scholar
  33. Tanaka H, Monahan KD, Seals DR (2001) Age-predicted maximal heart rate revisited. J Am Coll Cardiol 37:153–156.  https://doi.org/10.1016/S0735-1097(00)01054-8 CrossRefGoogle Scholar
  34. Tudor-Locke C, Leonardi C, Johnson WD et al (2011) Accelerometer steps/day translation of moderate-to-vigorous activity. Prev Med 53:31–33.  https://doi.org/10.1016/j.ypmed.2011.01.014 CrossRefGoogle Scholar
  35. Vickers AJ, Altman DG (2001) Statistics notes: analysing controlled trials with baseline and follow up measurements. BMJ 323:1123–1124CrossRefGoogle Scholar
  36. Villelabeitia-Jaureguizar K, Vicente-Campos D, Senen AB et al (2017) Effects of high-intensity interval versus continuous exercise training on post-exercise heart rate recovery in coronary heart-disease patients. Int J Cardiol 244:17–23.  https://doi.org/10.1016/j.ijcard.2017.06.067 CrossRefGoogle Scholar
  37. Watson AM, Brickson SL, Prawda ER, Sanfilippo JL (2017) Short-term heart rate recovery is related to aerobic fitness in elite intermittent sport athletes. J Strength Cond Res 31:1055.  https://doi.org/10.1519/JSC.0000000000001567 CrossRefGoogle Scholar
  38. West Suitor C, Kraak V, National Research Council (2007) Adequacy of evidence for physical activity guidelines development: workshop summary. The National Academic Press, Washington, DCGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Pennington Biomedical Research CenterBaton RougeUSA
  2. 2.Louisiana State UniversityBaton RougeUSA
  3. 3.ACAP HealthDallasUSA

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