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Capsaicin supplementation increases time to exhaustion in high-intensity intermittent exercise without modifying metabolic responses in physically active men

  • Marcelo Conrado de Freitas
  • François Billaut
  • Valéria Leme Gonçalves Panissa
  • Fabricio Eduardo Rossi
  • Caique Figueiredo
  • Erico Chagas Caperuto
  • Fabio Santos LiraEmail author
Original Article

Abstract

Purpose

The purpose of this study was to investigate the acute effect of capsaicin supplementation on performance and physiological responses during high-intensity intermittent exercise (HIIE).

Method

Thirteen physically active men (age = 24.4 ± 4.0 years; height = 176.4 ± 6.9 cm; body mass  =  78.7 ± 13.8 kg; running training per week = 3.9 ± 0.9 h) performed an incremental running test to determine peak oxygen uptake (\(\dot {V}{{\text{O}}_{{\text{2Peak}}}}\)) and the speed associated with \(\dot {V}{{\text{O}}_{{\text{2Peak}}}}\) (s\(\dot {V}{{\text{O}}_{{\text{2Peak}}}}\)). Thereafter, subjects completed two randomized, double-blind HIIE (15s:15 s at 120% s\(\dot {V}{{\text{O}}_{{\text{2Peak}}}}\)) trials 45-min after consuming capsaicin (12 mg) or an isocaloric placebo. Time to exhaustion, blood lactate concentration, oxygen consumption during and 20 min post-exercise, energy expenditure, time spent above 90% of \(\dot {V}{{\text{O}}_{{\text{2Peak}}}}\), and the rate of perceived exertion were evaluated.

Results

There was no difference between capsaicin and placebo for any variable except time to exhaustion [capsaicin: 1530 ± 515 s (102 efforts) vs placebo: 1342 ± 446 s (89 efforts); p < 0.001].

Conclusion

In conclusion, capsaicin supplementation increased time to exhaustion in high-intensity intermittent exercise without modifying the metabolic response of exercise or the rate of perceived exertion in physically active men. Capsaicin could be used to increase the training load during specific exercise training sessions.

Keywords

Excess post-oxygen consumption Lactate Energy system contribution 

Abbreviations

CAP

Capsaicin

EPOC

Excess of post-exercise oxygen consumption

HIIE

High-intensity intermittent exercise

RPE

Rate of perceived exertion

s\(\dot {V}{{\text{O}}_{{\text{2Peak}}}}\)

Speed associated with \(\dot {V}{{\text{O}}_{{\text{2Peak}}}}\)

TRPV1

Transient receptor potential vanilloid-1

\(\dot {V}{{\text{O}}_{{\text{2Peak}}}}\)

Peak oxygen uptake

Notes

Acknowledgements

This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code 001. We thank Dr. Alessandro Moura Zagatto (São Paulo State University—UNESP) for his critical reading of the manuscript.

Author contributions

Study design and organization of the manuscript were performed by MCF, FB, VLGP, FER, CF, EC, and FSL. Data analysis, statistical analysis, and the first draft of the manuscript were performed by MCF, VLGP, FER, FB, and FSL. The manuscript review was performed by MCF, FB, VLGP, FER, CF, EC, and FSL. The final approval for publication was performed by FSL.

Supplementary material

421_2019_4086_MOESM1_ESM.docx (20 kb)
Supplementary material 1 (DOCX 20 KB)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Marcelo Conrado de Freitas
    • 1
    • 7
  • François Billaut
    • 2
  • Valéria Leme Gonçalves Panissa
    • 3
  • Fabricio Eduardo Rossi
    • 4
  • Caique Figueiredo
    • 6
  • Erico Chagas Caperuto
    • 5
  • Fabio Santos Lira
    • 6
    Email author
  1. 1.Skeletal Muscle Assessment Laboratory (LABSIM), Department of Physical Education, School of Technology and SciencesSão Paulo State University (UNESP)Presidente PrudenteBrazil
  2. 2.Department of KinesiologyLaval UniversityQuebecCanada
  3. 3.Department of Sport, School of Physical Education and SportUniversity of São PauloSão PauloBrazil
  4. 4.Immunometabolism of Skeletal Muscle and Exercise Research GroupFederal University of Piauí (UFPI)TeresinaBrazil
  5. 5.University São Judas TadeuSão PauloBrazil
  6. 6.Exercise and Immunometabolism Research Group, Department of Physical EducationSão Paulo State University (UNESP)Presidente PrudenteBrazil
  7. 7.Department of NutritionUniversity of Western São Paulo (UNOESTE)Presidente PrudenteBrazil

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