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Effects of commodity on the risk of emphysema in South African miners

  • Sithembile L. MabilaEmail author
  • Kirsten S. Almberg
  • Lee Friedman
  • Robert A. Cohen
  • Ntombizodwa Ndlovu
  • Naseema Vorajee
  • Jill Murray
Original Article
  • 19 Downloads

Abstract

Purpose

To examine associations between mine commodity such as coal, platinum, or diamonds and emphysema among South African miners at autopsy.

Methods

We examined the association between mine commodity and emphysema using the Pathology Automation (PATHAUT) database, 1975–2014. Exposure was characterized as longest tenure in each commodity. We constructed separate multivariable logistic regression models for black and white miners. Smoking was assessed in a sub-analysis of white miners.

Results

Among black miners, coal mining was significantly associated with increased odds of emphysema [OR = 2.39 (95% CI 1.86, 3.07)] when compared to gold mining. Asbestos was also associated with significantly increased odds of emphysema among black miners [OR = 1.47 (95% CI 1.01, 2.12)]. No associations between commodity and emphysema were observed among white miners. Cumulative years of exposure and age at death were significant predictors for emphysema for both black and white miners. Smoking was a significant predictor of emphysema in the sub-analysis of white miners with smoking information, but no effect of commodity was observed.

Conclusions

We observed a significant association between coal mining and emphysema among black miners. Adverse health effects of coal mining are evidenced by more than twofold increase in emphysema among black coal miners compared to gold miners. This suggests that South African Coal miners are exposed to high dust concentrations or more damaging components compared to other commodities, resulting in elevated risk of emphysema.

Keywords

Emphysema Mining Occupation Commodity South Africa PATHAUT 

Notes

Funding

The research and researchers were supported in part by the National Institute of Occupational Safety and Health (NIOSH) Training Program Grant # T42/OH008672.

Conflict of interest

All authors have declared that they have no conflicts of interest that may be relevant to the submitted work.

Supplementary material

420_2019_1483_MOESM1_ESM.docx (15 kb)
Supplementary material 1 (DOCX 15 kb)
420_2019_1483_MOESM2_ESM.docx (36 kb)
Supplementary material 2 (DOCX 36 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Division of Environmental and Occupational Health Sciences, School of Public HealthUniversity of Illinois at ChicagoChicagoUSA
  2. 2.National Institute of Occupational HealthJohannesburgSouth Africa
  3. 3.School of Public HealthUniversity of WitwatersrandJohannesburgSouth Africa
  4. 4.School of PathologyUniversity of WitwatersrandJohannesburgSouth Africa

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