OCT angiography of the choroid in children with spontaneously regressed retinopathy of prematurity and children born preterm

  • Anna DastiridouEmail author
  • Maria Dermenoudi
  • Nikolaos Ziakas
  • Asimina Mataftsi
Letter to the Editor

Dear Editor,

The changes in choroidal thickness (ChT) in children with retinopathy of prematurity (ROP) and those born preterm have recently attracted scientific interest. It has been suggested that together with retina findings, ChT may represent a new biomarker to measure in these eyes since the choroid plays a major role in photoreceptors’ nutrition [1]. ChT has indeed been found reduced in ROP [2, 3, 4]. However, this finding was not replicated in a large population-based study [5]. In the present study, we used OCT angiography (OCTA) imaging to assess the microvasculature in the choriocapillaris layer in spontaneously regressed retinopathy of prematurity (srROP) and in children born preterm (preT) who did not develop ROP, in comparison with an age-matched control group with normal ophthalmologic exam.

We enrolled children born in 2010–2012 and excluded patients with retinal or cardiovascular disease, ocular trauma or surgery, and inadequate cooperation. The study adhered to the...



The authors thank Chara Tsiampali for her help in some eye examinations.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the Papageorgiou Hospital, Aristotle University of Thessaloniki research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Anna Dastiridou
    • 1
    Email author
  • Maria Dermenoudi
    • 1
  • Nikolaos Ziakas
    • 1
  • Asimina Mataftsi
    • 1
  1. 1.2nd Department of Ophthalmology, Medical School, “Papageorpiou” HospitalAristotle University of ThessalonikiThessalonikiGreece

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