Advertisement

Retinal detachment and uveitis at a tertiary center over 10 years: the King Khaled Eye Specialist Hospital (KKESH) Uveitis Survey Study Group

  • J. Fernando ArevaloEmail author
  • Andres F. Lasave
  • Turki Abdullah Al Ghamdi
  • Vishali Gupta
  • Igor Kozak
  • Hassan A. Al Dhibi
  • The KKESH Uveitis Survey Study Group
Retinal Disorders
  • 39 Downloads

Abstract

Purpose

To evaluate the frequency, etiology, treatment, and visual prognosis of retinal detachment (RD) in patients with uveitis.

Methods

A retrospective review was performed in 707 consecutive patients (1042 eyes) with uveitis, of whom 97 (13.7%) (157 eyes [15.1%]) had RD.

Results

There were 126 (12.1%) eyes with exudative retinal detachment (ERD), 16 (1.5%) with tractional retinal detachment (TRD), and 15 (1.4%) with rhegmatogenous retinal detachment (RRD). Panuveitis was most commonly associated with RD (144 (91.1%) eyes). Infectious causes were more common in RRD, and non-infectious etiologies were most common in ERD and TRD. Oral prednisone was the initial therapy in ERD. Additionally, in these cases, cyclosporine was prescribed most frequently (47.1% patients), followed by azathioprine (26.4% patients). Fourteen (87.5%) eyes with TRD and all RRD cases underwent surgery. In patients with ERD, the mean best-corrected visual acuity (BCVA) was 1.1 ± 0.7 LogMAR at baseline and 0.6 ± 0.2 LogMAR at last visit (p = 0.001). In patients with TRD, mean BCVA was 0.7 ± 0.4 LogMAR at baseline and 0.6 ± 0.4 LogMAR at last visit (p = 0.056). In patients with RRD, mean BCVA was 1.6 ± 0.9 LogMAR at baseline and 20 1.3 ± 0.9 LogMAR at last visit (p = 0.185).

Conclusion

In Saudi Arabia, ERD is observed in 12.1% of the eyes with uveitis, and less than 2% of eyes had TRD or RRD. Visual prognosis is usually good after ERD. Infection is the most frequent cause of RRD associated with uveitis and the visual prognosis is poor.

Keywords

Uveitis Retinal detachment Panuveitis Rhegmatogenous retinal detachment 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

References

  1. 1.
    Tomkins-Netzer O, Talat L, Bar A et al (2014) Long-term clinical outcome and causes of vision loss in patients with uveitis. Ophthalmology 121:2387–2392CrossRefGoogle Scholar
  2. 2.
    Kerkhoff FT, Lamberts QJ, van den Biesen PR et al (2003) Rhegmatogenous retinal detachment and uveitis. Ophthalmology 110:427–431CrossRefGoogle Scholar
  3. 3.
    Jabs DA, Nussenblatt RB, Rosenbaum JT, Standardization of Uveitis Nomenclature (SUN) Working Group (2005) Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol 140:509–516CrossRefGoogle Scholar
  4. 4.
    Nussenblatt RB, Palestine AG, Chan CC, Roberge F (1985) Standardization of vitreal inflammatory activity in intermediate and posterior uveitis. Ophthalmology 92:467–471CrossRefGoogle Scholar
  5. 5.
    Jumper JM, Machemer R, Gallemore RP, Jaffe GJ (2000) Exudative retinal detachment and retinitis associated with acquired syphilitic uveitis. Retina 20:190–194CrossRefGoogle Scholar
  6. 6.
    Bowyer JD, Gormley PD, Seth R et al (1999) Choroidal tuberculosis diagnosed by polymerase chain reaction. A clinicopathologic case report. Ophthalmology 106:290–294CrossRefGoogle Scholar
  7. 7.
    Bialasiewicz AA, Ruprecht KW, Naumann GOH, Blenk H (1988) Bilateral diffuse choroiditis and exudative retinal detachments with evidence of Lyme disease. Am J Ophthalmol 105:419–420CrossRefGoogle Scholar
  8. 8.
    Kerkhoff FT, Rothova A (2000) Bartonella henselae associated uveitis and HLA-B27. Br J Ophthalmol:1125–1129Google Scholar
  9. 9.
    Thompson MJ, Albert DM (2005) Ocular tuberculosis. Arch Ophthalmol 123(6):844–849CrossRefGoogle Scholar
  10. 10.
    Pollack AL, McDonald HR, Johnson RN et al (2002) Peripheral retinoschisis and exudative retinal detachment in pars planitis. Retina 22:719–722CrossRefGoogle Scholar
  11. 11.
    Brockhurst RJ. (1981) Retinoschisis: complication of peripheral uveitis. Arch Ophthalmol 99: 1998–1999Google Scholar
  12. 12.
    Jalil A, Dhawahir-Scala FE, Jones NP (2010) Nonprogressive tractional inferior retinal elevation in intermediate uveitis. Ocul Immunol Inflamm 18:60–63CrossRefGoogle Scholar
  13. 13.
    De Hoog J, Ten Berge JC, Groen F, Rothova A (2017) Rhegmatogenous retinal detachment in uveitis. J Ophthalmic Inflamm Infect 7(1):22CrossRefGoogle Scholar
  14. 14.
    Hagler WS, Jarrett WH II, Chang M (1978) Rhegmatogenous retinal detachment following chorioretinal inflammatory disease. Am J Ophthalmol 86:373–379CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • J. Fernando Arevalo
    • 1
    Email author
  • Andres F. Lasave
    • 2
  • Turki Abdullah Al Ghamdi
    • 3
  • Vishali Gupta
    • 3
  • Igor Kozak
    • 3
  • Hassan A. Al Dhibi
    • 3
  • The KKESH Uveitis Survey Study Group
  1. 1.Retina Division, Wilmer Eye InstituteJohns Hopkins University School of MedicineBaltimoreUSA
  2. 2.Retina and Vitreous ServiceClinica Privada de OjosMar del PlataArgentina
  3. 3.Uveitis DivisionKing Khaled Eye Specialist HospitalRiyadhKingdom of Saudi Arabia

Personalised recommendations