Journal of Neurology

, Volume 265, Issue 11, pp 2740–2742 | Cite as

Vertigo and impaired pursuit eye movements in a small medial superior temporal infarction

  • Jeong-Min Kim
  • Seog Kyun Mun
  • Il-Han Yoo
  • Christophe Lopez
  • Ji-Soo KimEmail author
Letter to the Editors

Dear Sirs,

Vertigo may occur in lesions involving the cerebral hemispheric regions such as the insular cortex, retroinsular area and temporo-parietal junction [1]. However, no study has described vertigo and impaired pursuit eye movements as the only findings of supratentorial strokes. We report isolated vertigo and impaired pursuit eye movements to the lesion side in a patient with a small infarction restricted to the deep white matter of left superior temporal gyrus. This report suggests the subcortical location of the fibers to and from the human homologue of parieto-insular vestibular cortex and medial superior temporal (MST) area in monkeys.

A 75-year-old woman reported two episodes of spontaneous vertigo with illusory self-motion lasting several minutes. She denied associated headache, diplopia, dysarthria, visual field defects or limb weakness/sensory disturbance. She had a history of left cerebellar infarction 5 years before, but without neurological sequelae and had been...



This study was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (no. NRF-2016R1D1A1B04935568).

Author contributions

J-MK analyzed and interpreted data and wrote the manuscript. SKM, I-HY and CL analyzed and interpreted data and revised manuscript. J-SK designed and conceptualized the study, interpreted the data, and revised the manuscript.

Compliance with ethical standards

Conflicts of interest

Jeong-Min Kim, Seog Kyun Mun, Il-Han Yoo and Christophe Lopez report no disclosure. Christophe Lopez serves as an associated editor of Frontiers in Integrative Neuroscience and guest editor of Frontiers in Neurology. Ji-Soo Kim serves as an associate editor of Frontiers in Neuro-otology and on the editorial boards of the Journal of Clinical Neurology, Frontiers in Neuro-ophthalmology, Journal of Neuro-ophthalmology, Journal of Vestibular Research, Journal of Neurology, and Medicine.

Ethical standards

This study was performed in accordance with the guidelines of Institutional Review Board of Chung-Ang University Hospital (C2013110-1070) and ethical standards laid down in the 1964 Declaration of Helsinki.


  1. 1.
    von Brevern M, Süßmilch S, Zeise D (2014) Acute vertigo due to hemispheric stroke: a case report and comprehensive review of the literature. J Neurol Sci 339:153–156CrossRefGoogle Scholar
  2. 2.
    Lopez C, Blanke O (2011) The thalamocortical vestibular system in animals and humans. Brain Res Rev 67:119–146CrossRefGoogle Scholar
  3. 3.
    Guldin WO, Grüsser OJ (1998) Is there a vestibular cortex? Trends Neurosci 21:254–259CrossRefGoogle Scholar
  4. 4.
    Heide W, Kurzidim K, Kömpf D (1996) Deficits of smooth pursuit eye movements after frontal and parietal lesions. Brain 119:1951–1969CrossRefGoogle Scholar
  5. 5.
    Petit L, Haxby JV (1999) Functional anatomy of pursuit eye movements in humans as revealed by fMRI. J Neurophysiol 82:463–471CrossRefGoogle Scholar
  6. 6.
    Choi SY, Kim Y, Oh SW, Jeong SH, Kim JS (2012) Pursuit-paretic and epileptic nystagmus in MELAS. J Neuroopthalmol 32:135–138CrossRefGoogle Scholar
  7. 7.
    Smith AT, Wall MB, Thilo KV (2012) Vestibular inputs to human motion-sensitive visual cortex. Cereb Cortex 22:1068–1077CrossRefGoogle Scholar
  8. 8.
    Lee SU, Suh HI, Choi JY, Huh K, Kim HJ, Kim JS (2014) Epileptic nystagmus: a case report and systematic review. Epilepsy Behav Case Rep 2:156–160CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of NeurologyChung-Ang University HospitalSeoulRepublic of Korea
  2. 2.Department of OtorhinolaryngologyChung-Ang University HospitalSeoulRepublic of Korea
  3. 3.Centre National de la Recherhe ScientifiqueAix-Marseille Université, LNSCMarseilleFrance
  4. 4.Department of Neurology, Dizziness Center, Clinical Neuroscience CenterSeoul National University College of Medicine, Seoul National University Bundang HospitalSeongnamRepublic of Korea

Personalised recommendations