Fatal cervix rupture due to intraplacental choriocarcinoma triggered by sexual intercourse
A 27-year-old woman, gravida 1 para 0, died 30 min after intercourse at the 16th week of gestation. The prenatal medical history indicated the placental implantation position at the cervix. The autopsy revealed massive hemoperitoneum and a tumor in the placenta and myometrium on the anterior right side of the cervix. A transmural perforation was found from the tumor to the serosal surface of the cervix. The autopsy, histopathology, and medical history indicated that her death was ascribed to the rupture of the cervix due to intraplacental choriocarcinoma (IC) after intercourse. The case indicated that placental implantation and tumor invasion might lead to the rupture of the uterus triggered by external forces in daily life. This case study might increase the awareness and recognition of IC.
KeywordsForensic pathology Cervix rupture Intraplacental choriocarcinoma Sudden unexpected death
This study was financially supported by the open project of Evidence-Identifying Key Laboratory in Shandong Universities of Political Science and Law (Grant 2018KFKT1).
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
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