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Genetic analysis and forensic evaluation of 47 autosomal InDel markers in four different Chinese populations

  • Xiyong Pan
  • Changhui Liu
  • Weian Du
  • Ling Chen
  • Xiaolong Han
  • Xingyi Yang
  • Chao LiuEmail author
Population Data
  • 12 Downloads

Abstract

This study aims to investigate the population-wide genetic data and forensic efficiency of 47 autosomal InDels in the four Chinese populations of Chinese Han, Tibetan, Uighur, and Chinese Hui. The allele frequencies and forensic parameters of the 47 InDels were investigated in 638 unrelated individuals from these four populations. The results can serve as a reference database that includes InDels in the populations, and they can contribute to population diversity studies.

Keywords

Forensic efficiency Insertion/deletion polymorphism Chinese populations Population genetics 

Notes

Acknowledgements

The authors are very grateful to all sample donors for their contributions to this work and all those who helped with sample collection. This study was supported by the Science and Technology Program of Guangzhou, China (grant numbers 201605131210203 and 201707010486).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

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Figure S1

Linkage disequilibrium analysis for 47 autosomal InDels in the four populations. A: Chinese Han population. B: Tibetan population. C: Uighur population. D: Chinese Hui population. (PNG 121 kb)

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Figure S2

The allele frequencies of the 47 autosomal InDels in the four populations. A: Chinese Han population. B: Tibetan population. C: Uighur population. D: Chinese Hui population. (PNG 149 kb)

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Figure S3

The forensic statistical parameters of the 47 autosomal InDel markers in the four Chinese populations. A: Expected heterozygosity. B: Observed heterozygosity. C: Polymorphism information content. D: Typical paternity index of the four population. (PNG 288 kb)

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Supplementary Table 1 (DOCX 29 kb)
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Supplementary Table 2 (DOCX 35 kb)
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Supplementary Table 3 (DOCX 28 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Xiyong Pan
    • 1
    • 2
  • Changhui Liu
    • 3
  • Weian Du
    • 4
  • Ling Chen
    • 5
  • Xiaolong Han
    • 3
  • Xingyi Yang
    • 3
  • Chao Liu
    • 3
    Email author
  1. 1.Faculty of Forensic Medicine, Zhongshan School of MedicineSun Yat-Sen UniversityGuangzhouChina
  2. 2.Forensic Science Center of Yuexiu District BranchGuangzhou Public Security Bureau in GuangDong ProvinceGuangzhouChina
  3. 3.Guangzhou Forensic Science InstituteGuangzhouChina
  4. 4.AGCU ScienTech IncorporationWuxiChina
  5. 5.School of Forensic MedicineSouthern Medical UniversityGuangzhouChina

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