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Allele frequencies of 15 autosomal STRs in Chinese Nakhi and Yi populations

  • Guanglin He
  • Yongdong Su
  • Xing Zou
  • Mengge Wang
  • Jing Liu
  • Shouyu Wang
  • Yiping Hou
  • Zheng Wang
Population Data

Abstract

Genetic characterization of ethnically and geographically diverse populations via short tandem repeats (STRs) is relevant to various fundamental and applied areas of forensic genetics, population studies, and even molecular anthropology. In the present study, genetic polymorphisms of 15 autosomal STR loci were firstly obtained from 918 individuals (495 Nakhis and 423 Yis) residing in the foothills of the Himalayas. The cumulative powers of discrimination and probabilities of exclusion in the two studied ethnic groups were both larger than 0.999999999999999982 and 0.9999961, respectively. Genetic similarities and differences among 61 populations were subsequently investigated by pairwise Cavalli-Sforza genetic distance, multidimensional scaling plots, principal component analysis, and phylogenetic relationship reconstruction. Both Nakhi and Yi had the genetically close relationships with Yunnan Bai and distinct relationships with Xinjiang Turkic-speaking populations (Uyghur and Kazakh) and Vietnamese.

Keywords

Short tandem repeat (STR) Genetic polymorphism Nakhi Yi Forensic genetics 

Notes

Funding information

This study received the support of grants from the National Key R&D Program of China (2016YFC0800703), the National Natural Science Foundation of China (81571854 and 81501635), and the Fundamental Research Funds for the Central Universities (20826041A4408, YJ201651, and 2012017yjsy187).

Compliance with ethical standards

Human blood samples were collected with the approval of the Ethics Committee of Sichuan University (Approval Number: K2015008).

Competing interests

The authors declare that they have no competing interests.

Supplementary material

414_2018_1931_MOESM1_ESM.xlsx (190 kb)
ESM 1 (XLSX 190 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Institute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic MedicineSichuan UniversityChengduChina
  2. 2.Forensic Identification CenterPublic Security Bureau of Tibet Autonomous RegionLhasaChina

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